Background Multiphoton microscopy (MPM) offers a feasible approach for the biopsy in
clinical medicine, but it has not been used in clinical applications due to the lack of efficient …

Understanding the delivery and diffusion of topically-applied drugs on human skin is of
paramount importance in both pharmaceutical and cosmetics research. This information is …

This review summarizes the historical and more recent developments of multiphoton
microscopy, as applied to dermatology. Multiphoton microscopy offers several advantages …

Quantifying skin aging changes and characterizing its 3D structure and function in a non-
invasive way is still a challenging area of research, constantly evolving with the …

Abstract Epidermal three‐dimensional (3D) topography/quantification has not been
completely characterized yet. The recently developed line‐field confocal optical coherence …

Characterizing melanins in situ and determining their 3D z-epidermal distribution is
paramount for understanding physiological/pathological processes of melanin neosynthesis …

Quantitative biomarkers of facial skin ageing were studied from one hundred healthy
Caucasian female volunteers, aged 20–70 years, using in vivo 3D Line-field Confocal …

Chronological skin aging is associated with flattening of the dermal-epidermal junction
(DEJ), but to date no quantitative analysis focusing on the aging changes in the dermal …

Background Human skin is composed of the superimposition of tissue layers of various
thicknesses and components. Histological staining of skin sections is the benchmark …

Background Skin occlusion caused by the use of diapers or sanitary napkins often results in
irritant contact dermatitis. Furthermore, prolonged occlusion and exposure to body fluids are …