[HTML][HTML] The lymphatic vasculature in the 21st century: novel functional roles in homeostasis and disease

G Oliver, J Kipnis, GJ Randolph, NL Harvey - Cell, 2020 - cell.com
Mammals have two specialized vascular circulatory systems: the blood vasculature and the
lymphatic vasculature. The lymphatic vasculature is a unidirectional conduit that returns …

[HTML][HTML] Lymphatic vessel network structure and physiology

JW Breslin, Y Yang, JP Scallan, RS Sweat… - Comprehensive …, 2018 - ncbi.nlm.nih.gov
The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue,
which has the holistic function to maintain the local physiologic environment for every cell in …

Surgical treatment of lymphedema

MV Schaverien, CJ Coroneos - Plastic and reconstructive surgery, 2019 - journals.lww.com
Lymphedema affects up to 250 million people worldwide. The understanding of the
pathophysiology of the condition, however, is incomplete and a cure remains elusive. A …

Agonizing over engagement: SEA and the “death of environmentalism” debates

J Brown, J Dillard - Critical Perspectives on Accounting, 2013 - Elsevier
Social and environmental accounting (SEA) is currently going through a period of critical self-
analysis. Fundamental questions are being raised about how SEA should be defined, who …

Cancer-associated secondary lymphoedema

SG Rockson, V Keeley, S Kilbreath, A Szuba… - Nature reviews Disease …, 2019 - nature.com
Lymphoedema is an oedematous condition with a specific and complex tissue biology. In
the clinical context of cancer, the pathogenesis of lymphoedema ensues most typically from …

The unresolved pathophysiology of lymphedema

SH Azhar, HY Lim, BK Tan, V Angeli - Frontiers in physiology, 2020 - frontiersin.org
Lymphedema is the clinical manifestation of impaired lymphatic transport. It remains an
under-recognized and under-documented clinical condition that still lacks a cure. Despite …

Advances in lymphedema

SG Rockson - Circulation research, 2021 - Am Heart Assoc
Lymphedema is a common, complex, and inexplicably underappreciated human disease.
Despite a history of relative neglect by health care providers and by governmental health …

[HTML][HTML] VEGFR3 is required for button junction formation in lymphatic vessels

M Jannaway, D Iyer, DM Mastrogiacomo, K Li… - Cell reports, 2023 - cell.com
Lymphatic capillaries develop discontinuous cell-cell junctions that permit the absorption of
large macromolecules, chylomicrons, and fluid from the interstitium. While excessive …

[HTML][HTML] Pilot studies demonstrate the potential benefits of antiinflammatory therapy in human lymphedema

SG Rockson, W Tian, X Jiang, T Kuznetsova… - JCI insight, 2018 - ncbi.nlm.nih.gov
BACKGROUND. Lymphedema is a common condition affecting millions around the world
that still lacks approved medical therapy. Because ketoprofen, an NSAID, has been …

Considerations for clinicians in the diagnosis, prevention, and treatment of breast cancer-related lymphedema: recommendations from a multidisciplinary expert …

SA McLaughlin, AC Staley, F Vicini… - Annals of surgical …, 2017 - Springer
Objective Diagnosing lymphedema is challenging, especially in the early stages (stage 0 or
1; Table 2) of the disease, with varying definitions and objective tools available for …