The molecular mechanisms of spinocerebellar ataxias for DNA repeat expansion in disease
Spinocerebellar ataxias (SCAs) are a heterogenous group of neurodegenerative disorders
which commonly inherited in an autosomal dominant manner. They cause muscle …
which commonly inherited in an autosomal dominant manner. They cause muscle …
An Updated Canvas of the RFC1-mediated CANVAS (Cerebellar Ataxia, Neuropathy and Vestibular Areflexia Syndrome)
Proliferation of specific nucleotide sequences within the coding and non-coding regions of
numerous genes has been implicated in approximately 40 neurodegenerative disorders …
numerous genes has been implicated in approximately 40 neurodegenerative disorders …
Triplex H-DNA structure: the long and winding road from the discovery to its role in human disease
JA Hisey, C Masnovo, SM Mirkin - NAR Molecular Medicine, 2024 - academic.oup.com
H-DNA is an intramolecular DNA triplex formed by homopurine-homopyrimidine mirror
repeats. Since its discovery, the field has advanced from characterizing the structure in vitro …
repeats. Since its discovery, the field has advanced from characterizing the structure in vitro …
[PDF][PDF] Fenotypowa i genotypowa charakterystyka zespołu CANVAS
F Tomczuk, A Sułek, IP i Neurologii - researchgate.net
Choroby neurodegeneracyjne to grupa zaburzeń wpływających na ośrodkowy układ
nerwowy, które prowadzące do postępującej utraty i dysfunkcji neuronów [1]. Większość z …
nerwowy, które prowadzące do postępującej utraty i dysfunkcji neuronów [1]. Większość z …