Summary Uncommitted (naive) murine CD4+ T helper cells (Thp) can be induced to
differentiate towards T helper 1 (Th1), Th2, Th17 and regulatory (Treg) phenotypes …

NKT cells are a relatively newly recognized member of the immune community, with
profound effects on the rest of the immune system despite their small numbers. They are true …

B cells perform many immunological functions, including presenting lipid antigen to CD1d-
restricted invariant natural killer T (iNKT) cells, known to contribute to maintaining tolerance …

CD1-and MHC-related molecule-1 (MR1)-restricted T lymphocytes recognize nonpeptidic
antigens, such as lipids and small metabolites, and account for a major fraction of circulating …

Natural killer T (NKT) cells are innate-like T lymphocytes that recognize glycolipid antigens
in the context of the MHC class I-related glycoprotein CD1d. Recent studies have identified …

Natural killer T (NKT) cells are an unusual subset of innate immune cells that express a
surface receptor generated by somatic DNA rearrangement, a hallmark of cells of the …

Abstract OTHER ARTICLES PUBLISHED IN THIS MINI-REVIEW SERIES ON Th17 CELLS
Function and regulation of human T helper 17 cells in health and disease. Clin Exp Immunol …

Although B cells play a pathogenic role in the initiation of type 1 diabetes (T1D) in NOD
mice, it is not known whether activated B cells can maintain tolerance and transfer protection …

NKT cells are true Ag-specific T cells that also have innate properties and form a bridge
between the innate and adaptive immune systems. Distinct NKT cell subsets play positive …

Diabetic kidney disease (DKD) is the most common cause of end-stage renal disease and
has gradually become a public health problem worldwide. DKD is increasingly recognized …