[HTML][HTML] Menstruation: science and society

HOD Critchley, E Babayev, SE Bulun, S Clark… - American journal of …, 2020 - Elsevier
Women's health concerns are generally underrepresented in basic and translational
research, but reproductive health in particular has been hampered by a lack of …

Uterine bleeding: how understanding endometrial physiology underpins menstrual health

V Jain, RR Chodankar, JA Maybin… - Nature reviews …, 2022 - nature.com
Menstruation is a physiological process that is typically uncomplicated. However, up to one
third of women globally will be affected by abnormal uterine bleeding (AUB) at some point in …

[HTML][HTML] Physiology of the endometrium and regulation of menstruation

HOD Critchley, JA Maybin… - Physiological …, 2020 - journals.physiology.org
The physiological functions of the uterine endometrium (uterine lining) are preparation for
implantation, maintenance of pregnancy if implantation occurs, and menstruation in the …

Uterine fibroids: burden and unmet medical need

A Al-Hendy, ER Myers, E Stewart - Seminars in reproductive …, 2017 - thieme-connect.com
Uterine fibroids affect a wide cross-section of the population, with prevalence, symptom
severity, and overall disease burden generally higher among black women, likely due to …

[HTML][HTML] Role of medical therapy in the management of uterine adenomyosis

S Vannuccini, S Luisi, C Tosti, F Sorbi, F Petraglia - Fertility and sterility, 2018 - Elsevier
Adenomyosis is a benign uterine condition affecting women at various ages with different
symptoms. The management of these patients is still controversial. Few clinical studies …

Progesterone receptor ligands for the treatment of endometriosis: the mechanisms behind therapeutic success and failure

FM Reis, LM Coutinho, S Vannuccini… - Human …, 2020 - academic.oup.com
BACKGROUND Despite intense research, it remains intriguing why hormonal therapies in
general and progestins in particular sometimes fail in endometriosis. OBJECTIVE AND …

Current medical therapy for adenomyosis: from bench to Bedside

A Etrusco, F Barra, V Chiantera, S Ferrero, S Bogliolo… - Drugs, 2023 - Springer
Adenomyosis, characterized by the growth of endometrial tissue within the uterine wall,
poses significant challenges in treatment. The literature primarily focuses on managing …

Progesterone signaling and uterine fibroid pathogenesis; molecular mechanisms and potential therapeutics

M Ali, M Ciebiera, S Vafaei, S Alkhrait, HY Chen… - Cells, 2023 - mdpi.com
Uterine fibroids (UFs) are the most important benign neoplastic threat to women's health
worldwide, with a prevalence of up to 80% in premenopausal women, and can cause heavy …

Uterine fibroids: an update on current and emerging medical treatment options

M Farris, C Bastianelli, E Rosato, I Brosens… - … and clinical risk …, 2019 - Taylor & Francis
Uterine fibroids are the most common gynecological disorder, classically requiring surgery
when symptomatic. Although attempts at finding a nonsurgical cure date back to centuries, it …

Selective progesterone receptor modulators (SPRMs) for uterine fibroids

A Murji, L Whitaker, TL Chow… - Cochrane Database of …, 2017 - cochranelibrary.com
Background Uterine fibroids are smooth muscle tumours arising from the uterus. These
tumours, although benign, are commonly associated with abnormal uterine bleeding, bulk …