The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

Abstract Novel coronavirus disease 2019 (COVID‐19) poses a global threat, due to its
fluctuating frequency and lethality. Published data revealed associations of COVID‐19 …

The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
current coronavirus disease 2019 (COVID-19) pandemic, affecting more than 219 countries …

Background COVID-19 is associated with several risk factors such as distinct ethnicities
(genetic ancestry), races, sexes, age, pre-existing comorbidities, smoking, and genetics. The …

Although advanced age and presence of comorbidities significantly impact the variation
observed in the clinical symptoms of COVID-19, it has been suggested that genetic variants …

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative
agent of coronavirus disease 2019 (COVID-19), was first identified in Eastern Asia (Wuhan …

Although advanced age, male sex, and some comorbidities impact the clinical course of
COVID-19, these factors only partially explain the inter-individual variability in disease …

It has been known for many years that the angiotensin-converting enzyme 2 (ACE2) is a cell
surface enzyme involved in the regulation of blood pressure. More recently, it was proven …

Background Some human polymorphisms of ACE1, ACE2, IFITM3, TMPRSS2 and TNFα
genes may have an effect on the susceptibility to SARS-CoV-2 infection and increase the …