The kinase NEK6 positively regulates LSD1 activity and accumulation in local chromatin sub-compartments
F Knodel, J Eirich, S Pinter, SA Eisler… - Communications …, 2024 - nature.com
LSD1 plays a crucial role in mammalian biology, regulated through interactions with
coregulators and post-translational modifications. Here we show that the kinase NEK6 …
coregulators and post-translational modifications. Here we show that the kinase NEK6 …
Autoregulatory mechanism of enzyme activity by the nuclear localization signal of lysine-specific demethylase 1
D Senanayaka, D Zeng, S Alishiri, WJ Martin… - Journal of Biological …, 2024 - jbc.org
The N-terminal region of the human lysine-specific demethylase 1 (LSD1) has no predicted
structural elements, contains a nuclear localization signal (NLS), undergoes multiple …
structural elements, contains a nuclear localization signal (NLS), undergoes multiple …