X-ray computed tomography in life sciences

SD Rawson, J Maksimcuka, PJ Withers, SH Cartmell - BMC biology, 2020 - Springer
Recent developments within micro-computed tomography (μCT) imaging have combined to
extend our capacity to image tissue in three (3D) and four (4D) dimensions at micron and …

Current strategies with implementation of three-dimensional cell culture: the challenge of quantification

J Temple, E Velliou, M Shehata, R Lévy… - Interface …, 2022 - royalsocietypublishing.org
From growing cells in spheroids to arranging them on complex engineered scaffolds, three-
dimensional cell culture protocols are rapidly expanding and diversifying. While these …

A micro-CT-based standard brain atlas of the bumblebee

L Rother, N Kraft, DB Smith, B El Jundi, RJ Gill… - Cell and Tissue …, 2021 - Springer
In recent years, bumblebees have become a prominent insect model organism for a variety
of biological disciplines, particularly to investigate learning behaviors as well as visual …

Imaging the mammary gland and mammary tumours in 3D: optical tissue clearing and immunofluorescence methods

B Lloyd-Lewis, FM Davis, OB Harris, JR Hitchcock… - Breast Cancer …, 2016 - Springer
Background High-resolution 3D imaging of intact tissue facilitates cellular and subcellular
analyses of complex structures within their native environment. However, difficulties …

X-ray micro computed-tomography

E Baird, G Taylor - Current Biology, 2017 - cell.com
R290 Current Biology 27, R283–R293, April 24, 2017 to distinguish different structures if
they vary in their elemental composition or density. This means that, by using the right optics …

[HTML][HTML] MicroCT optimisation for imaging fascicular anatomy in peripheral nerves

N Thompson, E Ravagli, S Mastitskaya… - Journal of neuroscience …, 2020 - Elsevier
Background Due to the lack of understanding of the fascicular organisation, vagus nerve
stimulation (VNS) leads to unwanted off-target effects. Micro-computed tomography …

The relative compliance of energy-storing tendons may be due to the helical fibril arrangement of their fascicles

T Shearer, CT Thorpe… - Journal of the Royal …, 2017 - royalsocietypublishing.org
A nonlinear elastic microstructural model is used to investigate the relationship between
structure and function in energy-storing and positional tendons. The model is used to fit …

A review of techniques for visualising soft tissue microstructure deformation and quantifying strain Ex Vivo

CM Disney, PD Lee, JA Hoyland… - Journal of …, 2018 - Wiley Online Library
Many biological tissues have a complex hierarchical structure allowing them to function
under demanding physiological loading conditions. Structural changes caused by ageing or …

Novel approaches to characterize age‐related remodelling of the dermal‐epidermal junction in 2D, 3D and in vivo

VL Newton, RS Bradley, P Seroul… - Skin Research and …, 2017 - Wiley Online Library
Background/purpose The dermal‐epidermal junction (DEJ) forms epidermal protrusions
down into the dermis (rete ridges) and dermal projections up into the epidermis (dermal …

Detection of nephrocalcinosis using ultrasonography, micro‐computed tomography, and histopathology in cats

PK Tang, RF Geddes, YM Chang… - Journal of Veterinary …, 2024 - Wiley Online Library
Background Identification of nephrocalcinosis in cats with chronic kidney disease (CKD) is of
clinical interest but the ability of ultrasonography to detect nephrocalcinosis is uncertain …