Collagen-binding peptides for the enhanced imaging, lubrication and regeneration of osteoarthritic articular cartilage

CY Lin, YL Wang, YJ Chen, CT Ho, YH Chi… - Nature Biomedical …, 2022 - nature.com
Treatments for osteoarthritis would benefit from the enhanced visualization of injured
articular cartilage and from the targeted delivery of disease-modifying drugs to it. Here, by …

The SUSTech-SYSU dataset for automatically segmenting and classifying corneal ulcers

L Deng, J Lyu, H Huang, Y Deng, J Yuan, X Tang - Scientific data, 2020 - nature.com
Corneal ulcer is a common ophthalmic symptom. Segmentation algorithms are needed to
identify and quantify corneal ulcers from ocular staining images. Developments of such …

Cyclosporin A improves the hyperosmotic response in an experimental dry eye model by inhibiting the HMGB1/TLR4/NF-κB signaling pathway

J Shen, Y Liang, Z Bi, X Yin, C Chen, X Zhao… - Experimental Eye …, 2023 - Elsevier
Hyperosmolarity is closely related to dry eye disease (DED), which induces corneal
epithelial cell structure and dysfunction leading to ocular surface inflammation. Cyclosporine …

Multi-scale information fusion network with label smoothing strategy for corneal ulcer classification in slit lamp images

L Lv, M Peng, X Wang, Y Wu - Frontiers in Neuroscience, 2022 - frontiersin.org
Corneal ulcer is the most common symptom of corneal disease, which is one of the main
causes of corneal blindness. The accurate classification of corneal ulcer has important …

Automatic classification for corneal ulcer using a modified VGG network

N Tang, H Liu, K Yue, W Li… - … Conference on Artificial …, 2020 - ieeexplore.ieee.org
Deep learning techniques are more and more used for automatic classification of corneal
ulcer. A modified VGG framework for corneal ulcer classification was proposed to realize …

Automatic corneal ulcer segmentation combining Gaussian mixture modeling and Otsu method

Z Liu, Y Shi, P Zhan, Y Zhang, Y Gong… - 2019 41st Annual …, 2019 - ieeexplore.ieee.org
In this paper, we proposed and validated a novel and accurate pipeline for automatically
segmenting flaky corneal ulcer areas from fluorescein staining images. The ulcer area was …

Superpixel based automatic segmentation of corneal ulcers from ocular staining images

L Deng, H Huang, J Yuan… - 2018 IEEE 23rd …, 2018 - ieeexplore.ieee.org
In this paper, we proposed and validated a novel and accurate automatic pipeline for
extracting flaky corneal ulcer areas based on fluorescein staining images. We first used an …

Variability of dry eye disease following removal of lacrimal glands in rats

J Skrzypecki, H Tomasz, C Karolina - Medical Science and Research, 2019 - Springer
Removal of lacrimal glands is used as a viable model of dry eye disease in rats. However,
there is no uniform agreement on the disease severity following different variants of the …

[HTML][HTML] Sjögren's Versus Non-Sjögren's Ocular Features: Similar Symptoms, But Significantly Worse Signs

F Xiong, D Pula, EK Akpek, VY Bunya… - … & visual science, 2024 - jov.arvojournals.org
Purpose: To examine the ocular signs and symptoms in participants of the Sjögren's
International Collaborative Clinical Alliance cohort, and to compare them across Sjögren's …

[HTML][HTML] Three cases of acute sterile corneal melt after cataract surgery

K Harada, YH Mohamed, M Uematsu, D Inoue… - American journal of …, 2019 - Elsevier
Purpose To report three cases of acute sterile corneal melt after cataract surgery.
Observations Case 1 was a 21-year-old male presenting with a corneal perforation of his …