Fabrication of biomedical scaffolds using biodegradable polymers

A Kirillova, TR Yeazel, D Asheghali… - Chemical …, 2021 - ACS Publications
Degradable polymers are used widely in tissue engineering and regenerative medicine.
Maturing capabilities in additive manufacturing coupled with advances in orthogonal …

The evolution of tissue engineered vascular graft technologies: from preclinical trials to advancing patient care

Y Matsuzaki, K John, T Shoji, T Shinoka - Applied Sciences, 2019 - mdpi.com
Currently available synthetic grafts have contributed to improved outcomes in cardiovascular
surgery. However, the implementation of these graft materials at small diameters have …

Bioengineered human acellular vessels recellularize and evolve into living blood vessels after human implantation

RD Kirkton, M Santiago-Maysonet, JH Lawson… - Science translational …, 2019 - science.org
Traditional vascular grafts constructed from synthetic polymers or cadaveric human or
animal tissues support the clinical need for readily available blood vessels, but often come …

[HTML][HTML] Functionalization of in vivo tissue-engineered living biotubes enhance patency and endothelization without the requirement of systemic anticoagulant …

H Yan, Q Cheng, J Si, S Wang, Y Wan, X Kong… - Bioactive Materials, 2023 - Elsevier
Vascular regeneration and patency maintenance, without anticoagulant administration,
represent key developmental trends to enhance small-diameter vascular grafts (SDVG) …

Spontaneous reversal of stenosis in tissue-engineered vascular grafts

JD Drews, VK Pepper, CA Best, JM Szafron… - Science translational …, 2020 - science.org
We developed a tissue-engineered vascular graft (TEVG) for use in children and present
results of a US Food and Drug Administration (FDA)–approved clinical trial evaluating this …

Artificial scaffolds in cardiac tissue engineering

JA Roacho-Pérez, EN Garza-Treviño… - Life, 2022 - mdpi.com
Cardiovascular diseases are a leading cause of death worldwide. Current treatments
directed at heart repair have several disadvantages, such as a lack of donors for heart …

Systematic review of tissue-engineered vascular grafts

D Durán-Rey, V Crisóstomo… - … in bioengineering and …, 2021 - frontiersin.org
Pathologies related to the cardiovascular system are the leading causes of death worldwide.
One of the main treatments is conventional surgery with autologous transplants. Although …

Tissue engineered vascular grafts transform into autologous neovessels capable of native function and growth

KM Blum, JC Zbinden, AB Ramachandra… - Communications …, 2022 - nature.com
Background Tissue-engineered vascular grafts (TEVGs) have the potential to advance the
surgical management of infants and children requiring congenital heart surgery by creating …

Hemodynamic performance of tissue-engineered vascular grafts in Fontan patients

EL Schwarz, JM Kelly, KM Blum, KN Hor… - NPJ Regenerative …, 2021 - nature.com
In the field of congenital heart surgery, tissue-engineered vascular grafts (TEVGs) are a
promising alternative to traditionally used synthetic grafts. Our group has pioneered the use …

Inflammation-directed nanozyme-eluting hydrogel coating promotes vascular tissue repair by restoring reactive oxygen species homeostasis

F Yang, G Guo, Y Wang - Chemical Engineering Journal, 2023 - Elsevier
Thrombosis and stenosis remain two of the most prevalent complications of vascular
implants. The most effective strategy in clinics to inhibit stenosis is based on the eluting of …