[HTML][HTML] Neuroprotective strategies for retinal ganglion cell degeneration: current status and challenges ahead

R Boia, N Ruzafa, ID Aires, X Pereiro… - International journal of …, 2020 - mdpi.com
The retinal ganglion cells (RGCs) are the output cells of the retina into the brain. In
mammals, these cells are not able to regenerate their axons after optic nerve injury, leaving …

[HTML][HTML] The role of endogenous neuroprotective mechanisms in the prevention of retinal ganglion cells degeneration

M Pietrucha-Dutczak, M Amadio, S Govoni… - Frontiers in …, 2018 - frontiersin.org
Retinal neurons are not able to undergo spontaneous regeneration in response to damage.
A variety of stressors, ie, UV radiation, high temperature, ischemia, allergens, and others …

Effect of patch size and network architecture on a convolutional neural network approach for automatic segmentation of OCT retinal layers

J Hamwood, D Alonso-Caneiro, SA Read… - Biomedical optics …, 2018 - opg.optica.org
Deep learning strategies, particularly convolutional neural networks (CNNs), are especially
suited to finding patterns in images and using those patterns for image classification. The …

Effect of repeated intravitreal injections in glaucoma spectrum diseases

R Vilares-Morgado, V Correia, AM Ferreira… - Clinical …, 2023 - Taylor & Francis
Purpose To evaluate whether repeated intravitreal injections (IVI) with an anti-vascular
endothelial growth factor (anti-VEGF) agent are associated with glaucomatous progression …

Rates of RNFL thinning in patients with suspected or confirmed glaucoma receiving unilateral intravitreal injections for exudative AMD

SS Swaminathan, AL Kunkler, AV Quan… - American journal of …, 2021 - Elsevier
Purpose This study evaluated whether the rate of retinal nerve fiber layer (RNFL) thinning is
faster in eyes receiving intravitreal injections than in fellow uninjected eyes among patients …

[HTML][HTML] Anterior chamber paracentesis during intravitreal injections in observational trials: effectiveness and safety and effects

S Saxena, TY Lai, H Koizumi, ME Farah… - International journal of …, 2019 - Springer
A paracentesis prior to an intravitreal injection is a very safe procedure and can prevent IOP-
spikes after injections. As these spikes pose the risk of inducing glaucomatous changes …

[HTML][HTML] Changes in inner retinal layer thickness in patients with exudative age-related macular degeneration during treatment with anti-vascular endothelial growth …

SW Lee, HE Sim, JY Park, JS Kim, IB Chang, YS Park… - Medicine, 2020 - journals.lww.com
The aim of this study was to identify any changes that occur in the retinal nerve fiber layer
(RNFL) and ganglion cell-inner plexiform layer (GC-IPL) in patients with exudative age …

Role of mammalian target of rapamycin in regulating HIF-1α and vascular endothelial growth factor signals in glaucoma

J Zhou, F Chen, A Yan, X Xia - Archives of Physiology and …, 2021 - Taylor & Francis
Hypoxia inducible factor subtype 1α (HIF-1α) in retinal tissues is involved in the
development of glaucoma. This study examined the role played by mammalian target of …

Anti-vascular endothelial growth factor intravitreal therapy and macular ganglion cell layer thickness in patients with neovascular age-related macular degeneration

S Abdolrahimzadeh, M Gharbiya, M Formisano… - Current eye …, 2019 - Taylor & Francis
Purpose To assess macular ganglion cell layer (GCL) thickness in patients treated with
intravitreal anti-vascular endothelial growth factor (anti-VEGF) for exudative age-related …

[HTML][HTML] The Anti-Inflammatory and Antioxidant Properties of Acebuche Oil Exert a Retinoprotective Effect in a Murine Model of High-Tension Glaucoma

M Lucchesi, S Marracci, R Amato, D Lapi… - Nutrients, 2024 - mdpi.com
Glaucoma is characterized by cupping of the optic disc, apoptotic degeneration of retinal
ganglion cells (RGCs) and their axons, and thinning of the retinal nerve fiber layer, with …