The Rise of Boron-Containing Compounds: Advancements in Synthesis, Medicinal Chemistry, and Emerging Pharmacology
Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …
[HTML][HTML] BODIPYs in antitumoral and antimicrobial photodynamic therapy: An integrating review
Nowadays, both cancer and infections caused by antibiotic resistant microorganisms are
problems that affect the entire planet. Phototherapy (namely photodynamic therapy (PDT) …
problems that affect the entire planet. Phototherapy (namely photodynamic therapy (PDT) …
BODIPY derivatives for photodynamic therapy: influence of configuration versus heavy atom effect
J Zou, Z Yin, K Ding, Q Tang, J Li, W Si… - … applied materials & …, 2017 - ACS Publications
Heavy atom effect and configuration are important for BODIPY derivatives to generate
singlet oxygen (1O2) for photodynamic therapy. Herein, a series of BODIPY derivatives with …
singlet oxygen (1O2) for photodynamic therapy. Herein, a series of BODIPY derivatives with …
BODIPYs to the rescue: Potential applications in photodynamic inactivation
Difluoro-4-bora-3a, 4a-diaza-s-indacene (BODIPY) derivatives have been proposed in
several potential biomedical applications. BODIPYs absorb strongly in blue-green region …
several potential biomedical applications. BODIPYs absorb strongly in blue-green region …
Penetration depth tunable BODIPY derivatives for pH triggered enhanced photothermal/photodynamic synergistic therapy
Improving the deep-tissue phototherapy (PDT) efficiency in the near-infrared (NIR) region
has become one of the major challenges in clinics for cancer treatment. Developing …
has become one of the major challenges in clinics for cancer treatment. Developing …
Photosensitizer synergistic effects: D–A–D structured organic molecule with enhanced fluorescence and singlet oxygen quantum yield for photodynamic therapy
The development of photosensitizers with high fluorescence intensity and singlet oxygen
(1O2) quantum yields (QYs) is of great importance for cancer diagnosis and photodynamic …
(1O2) quantum yields (QYs) is of great importance for cancer diagnosis and photodynamic …
Synthesis, spectroscopic properties and photodynamic activity of two cationic BODIPY derivatives with application in the photoinactivation of microorganisms
ML Agazzi, MB Ballatore, E Reynoso… - European Journal of …, 2017 - Elsevier
Two cationic BODIPYs 3 and 4 were synthesized by acid-catalyzed condensation of the
corresponding pyrrole and benzaldehyde, followed by complexation with boron and …
corresponding pyrrole and benzaldehyde, followed by complexation with boron and …
Design, synthesis, and utility of defined molecular scaffolds
A growing theme in chemistry is the joining of multiple organic molecular building blocks to
create functional molecules. Diverse derivatizable structures—here termed “scaffolds” …
create functional molecules. Diverse derivatizable structures—here termed “scaffolds” …
Metal coordination effects on the photophysics of dipyrrinato photosensitizers
Within this work, we review the metal coordination effect on the photophysics of metal
dipyrrinato complexes. Dipyrrinato complexes are promising candidates in the search for …
dipyrrinato complexes. Dipyrrinato complexes are promising candidates in the search for …
Photodynamic inactivation of microorganisms sensitized by cationic BODIPY derivatives potentiated by potassium iodide
E Reynoso, ED Quiroga, ML Agazzi… - Photochemical & …, 2017 - Springer
The photodynamic inactivation mediated by 1, 3, 5, 7-tetramethyl-8-[4-(N, N, N-
trimethylamino) phenyl]-4, 4-difluoro-4-bora-3a, 4a-diaza-s-indacene 3 and 8-[4-(3-(N, N, N …
trimethylamino) phenyl]-4, 4-difluoro-4-bora-3a, 4a-diaza-s-indacene 3 and 8-[4-(3-(N, N, N …