The skin, being the largest organ in the human body, is exposed to the environment and
suffers from both intrinsic and extrinsic aging factors. The skin aging process is …

Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …

The growing incidence of melanoma is a serious public health issue that merits a thorough
understanding of potential causative risk factors, which includes exposure to ultraviolet …

Background Sleep is important for growth and renewal of multiple physiological systems.
The effects of chronic poor sleep quality on human skin function and visible signs of ageing …

Historically, work on peripheral circadian clocks has been focused on organs and tissues
that have prominent metabolic functions, such as the liver, fat, and muscle. In recent years …

Melanocytes produce melanin to protect the skin from UV-B radiation. Notwithstanding, the
spectrum of their functions extends far beyond their well-known role as melanin production …

Skin cancers are growing in incidence worldwide and are primarily caused by exposures to
ultraviolet (UV) wavelengths of sunlight. UV radiation induces the formation of photoproducts …

The hair follicle (HF) is a continuously remodeled mini organ that cycles between growth
(anagen), regression (catagen), and relative quiescence (telogen). As the anagen-to …

Aging is a complex natural process that leads to a decline in physiological functions, which
is visible in signs such as hair graying, thinning, and loss. Although hair graying is …

Although the regulation of pigmentation is well characterized, it remains unclear whether cell-
autonomous controls regulate the cyclic on–off switching of pigmentation in the hair follicle …