[HTML][HTML] Obesity and type 2 diabetes mellitus: connections in epidemiology, pathogenesis, and treatments

R Ruze, T Liu, X Zou, J Song, Y Chen, R Xu… - Frontiers in …, 2023 - frontiersin.org
The prevalence of obesity and diabetes mellitus (DM) has been consistently increasing
worldwide. Sharing powerful genetic and environmental features in their pathogenesis …

Gut microbial metabolites in obesity, NAFLD and T2DM

EE Canfora, RCR Meex, K Venema… - Nature Reviews …, 2019 - nature.com
Evidence is accumulating that the gut microbiome is involved in the aetiology of obesity and
obesity-related complications such as nonalcoholic fatty liver disease (NAFLD), insulin …

[HTML][HTML] The short-chain fatty acid acetate in body weight control and insulin sensitivity

MA González Hernández, EE Canfora, JWE Jocken… - Nutrients, 2019 - mdpi.com
The interplay of gut microbiota, host metabolism, and metabolic health has gained increased
attention. Gut microbiota may play a regulatory role in gastrointestinal health, substrate …

Metabolites as regulators of insulin sensitivity and metabolism

Q Yang, A Vijayakumar, BB Kahn - Nature reviews Molecular cell …, 2018 - nature.com
The cause of insulin resistance in obesity and type 2 diabetes mellitus (T2DM) is not limited
to impaired insulin signalling but also involves the complex interplay of multiple metabolic …

Short-chain fatty acids in control of body weight and insulin sensitivity

EE Canfora, JW Jocken, EE Blaak - Nature Reviews Endocrinology, 2015 - nature.com
The connection between the gut microbiota and the aetiology of obesity and cardiometabolic
disorders is increasingly being recognized by clinicians. Our gut microbiota might affect the …

[HTML][HTML] The impact of artificial sweeteners on body weight control and glucose homeostasis

MD Pang, GH Goossens, EE Blaak - Frontiers in nutrition, 2021 - frontiersin.org
A poor diet is one of the leading causes for noncommunicable diseases. Due to the
increasing prevalence of overweight and obesity, there is a strong focus on dietary …

Dietary macronutrients and the gut microbiome: a precision nutrition approach to improve cardiometabolic health

KM Jardon, EE Canfora, GH Goossens, EE Blaak - Gut, 2022 - gut.bmj.com
Accumulating evidence indicates that the gut microbiome is an important regulator of body
weight, glucose and lipid metabolism, and inflammatory processes, and may thereby play a …

Short-chain fatty acids in control of energy metabolism

J Hu, S Lin, B Zheng, PCK Cheung - Critical reviews in food …, 2018 - Taylor & Francis
Short-chain fatty acids (SCFAs), especially acetate, propionate and butyrate, are the end
products from the intestinal microbial fermentation of dietary fibers and resistant starch. It has …

Short chain fatty acids in human gut and metabolic health

EE Blaak, EE Canfora, S Theis, G Frost… - Beneficial …, 2020 - wageningenacademic.com
Evidence is accumulating that short chain fatty acids (SCFA) play an important role in the
maintenance of gut and metabolic health. The SCFA acetate, propionate and butyrate are …

[HTML][HTML] Gut microbiota and gestational diabetes mellitus: a review of host-gut microbiota interactions and their therapeutic potential

Z Hasain, NM Mokhtar, NA Kamaruddin… - Frontiers in cellular …, 2020 - frontiersin.org
Gestational diabetes mellitus (GDM) is defined as impaired glucose tolerance recognized
during pregnancy. GDM is associated with metabolic disorder phenotypes, such as obesity …