Studies of brain network connectivity improved understanding on brain changes and
adaptation in response to different pathologies. Synaptic plasticity, the ability of neurons to …

The goal of this review article is to provide a resource for longitudinal studies, using animal
models, directed at understanding and modifying the relationship between cognition and …

Exposure to environmental enrichment can beneficially influence the behavior and enhance
synaptic plasticity. The aim of the present study was to investigate the mediated effects of …

Environmental enrichment (EE) is an environmental paradigm encompassing sensory,
cognitive, and physical stimulation at a heightened level. Previous studies have reported the …

Cumulative evidence shows that modifications in lifestyle factors constitute an effective
strategy to modulate molecular events related to neurodegenerative diseases, confirming …

The decline of brain function during aging is associated with epigenetic changes, including
DNA methylation. Lifestyle interventions can improve brain function during aging, but their …

Neuroplasticity accounts for the ability of the brain to change in both structure and function in
consequence of life experiences. An enhanced stimulation provided by the environment is …

Since the 1950s, researchers have examined how differences in the social and asocial
environment affect learning in rats, mice, and, more recently, a variety of other species …

Environmental enrichment is known to improve brain plasticity and protect synaptic function
from negative insults. In the present study we used the exposure to social enrichment to …

Methods A total of 45 aged male Wistar rats with an age of 20 months were randomly
assigned into five groups of control (C), swimming HIIT (SW-HIIT), swimming HIIT with …