Alpha-thalassemia resulting from deletion of regulatory sequences far upstream of the alpha-globin structural genes

L Romao, L Osorio-Almeida, DR Higgs, J Lavinha… - 1991 - ashpublications.org
We describe an alpha-thalassemia determinant in which alpha-globin expression is
silenced by a deletion located 27 kb 5′ to the transcription start site of the alpha 2-globin …

VpreB gene expression in hematopoietic malignancies: a lineage-and stage-restricted marker for B-cell precursor leukemias

SR Bauer, H Kubagawa, I Maclennan, F Melchers - 1991 - ashpublications.org
We show here that analysis of VpreB gene transcription can be a specific way to identify
acute leukemias of cells at very early stages of B-cell development. Northern blot analysis of …

[PDF][PDF] Alpha-thalassemia resulting from deletion of regulatory sequences far

L Romao, L Osorio-Almeida, DR Higgs, J Lavinha… - 2011 - researchgate.net
MATERIALS AND METHODS RNA isolation and analysis. RNA was isolated from peripheral
blood reticulocytes by phenol extraction of acid precipitated polysomes” and used without …

[PDF][PDF] MATERNAL AND CHILD HEALTH BUREAU

AA Knapp, DR Metterville, AR Kemper, L Prosser… - hrsa.gov
Neonatal hyperbilirubinemia is a term for elevated total serum bilirubin in newborns and
infants less than one month of age. Neonatal hyperbilirubinemia has multiple etiologies and …

[图书][B] Functional significance of the Simian virus 40 late mRNA polyadenylation signal RNA secondary structure

HH Henry - 2000 - search.proquest.com
The SV40 late polyadenylation signal (SVLPAS) is very efficient and characterized by its
structure which is more complex than most known mammalian polyadenylation (PA) signals …