Extracellular matrix in the trabecular meshwork: intraocular pressure regulation and dysregulation in glaucoma
The trabecular meshwork (TM) is located in the anterior segment of the eye and is
responsible for regulating the outflow of aqueous humor. Increased resistance to aqueous …
responsible for regulating the outflow of aqueous humor. Increased resistance to aqueous …
Exfoliation syndrome
R Ritch, U Schlötzer-Schrehardt - Survey of ophthalmology, 2001 - Elsevier
Exfoliation syndrome (XFS) is an age-related disease in which abnormal fibrillar
extracellular material is produced and accumulates in many ocular tissues. Its ocular …
extracellular material is produced and accumulates in many ocular tissues. Its ocular …
Aqueous humor in glaucomatous eyes contains an increased level of TGF-β2
RC Tripathi, J Li, WFA Chan, BJ Tripathi - Experimental eye research, 1994 - Elsevier
By using the highly sensitive and specific technique of enzyme-linked immunosorbent
assay, we investigated the presence and amount of transforming growth factor-β2 (TGF-β2) …
assay, we investigated the presence and amount of transforming growth factor-β2 (TGF-β2) …
Pathogenesis of glaucoma: Extracellular matrix dysfunction in the trabecular meshwork‐A review
KE Keller, DM Peters - Clinical & experimental ophthalmology, 2022 - Wiley Online Library
The trabecular meshwork regulates aqueous humour outflow from the anterior chamber of
the eye. It does this by establishing a tunable outflow resistance, defined by the interplay …
the eye. It does this by establishing a tunable outflow resistance, defined by the interplay …
Open-angle glaucoma
HA Quigley - New England Journal of Medicine, 1993 - Mass Medical Soc
Our understanding of glaucoma has undergone dramatic changes in the past decade. The
ferment has derived from new epidemiologic information, improved diagnostic methods, and …
ferment has derived from new epidemiologic information, improved diagnostic methods, and …
Extracellular matrix in the trabecular meshwork
The extracellular matrix (ECM) of the trabecular meshwork (TM) is thought to be important in
regulating intraocular pressure (IOP) in both normal and glaucomatous eyes. IOP is …
regulating intraocular pressure (IOP) in both normal and glaucomatous eyes. IOP is …
The role of TGF-β in the pathogenesis of primary open-angle glaucoma
R Fuchshofer, ER Tamm - Cell and tissue research, 2012 - Springer
Transforming growth factor-β2 (TGF-β2) is found in increasing amounts in aqueous humor
and reactive optic nerve astrocytes of patients with primary open-angle glaucoma (POAG), a …
and reactive optic nerve astrocytes of patients with primary open-angle glaucoma (POAG), a …
Changes in aqueous humor dynamics with age and glaucoma
PL Kaufman - Progress in retinal and eye research, 2005 - Elsevier
Changes in aqueous humor dynamics with age and in glaucoma have been studied for
several decades. More recently, techniques have been developed which confirm earlier …
several decades. More recently, techniques have been developed which confirm earlier …
[HTML][HTML] Multiplex cytokine analysis of aqueous humor in eyes with primary open-angle glaucoma, exfoliation glaucoma, and cataract
Y Takai, M Tanito, A Ohira - Investigative ophthalmology & …, 2012 - tvst.arvojournals.org
Purpose.: To measure levels of various inflammatory cytokines in the aqueous humor of
patients with primary open-angle glaucoma (POAG), exfoliation glaucoma (EXG), and senile …
patients with primary open-angle glaucoma (POAG), exfoliation glaucoma (EXG), and senile …
Current concepts in the pathophysiology of glaucoma
R Agarwal, SK Gupta, P Agarwal… - Indian journal of …, 2009 - journals.lww.com
Glaucoma, the second leading cause of blindness, is characterized by changes in the optic
disc and visual field defects. The elevated intraocular pressure was considered the prime …
disc and visual field defects. The elevated intraocular pressure was considered the prime …