Rotavirus infections are a leading cause of severe, dehydrating gastroenteritis in children< 5
years of age. Despite the global introduction of vaccinations for rotavirus over a decade ago …

A safe and effective rotavirus vaccine is urgently needed, particularly in developing
countries. Critical to vaccine development and implementation is a knowledge base …

Oral vaccines are less immunogenic when given to infants in low-income compared with
high-income countries, limiting their potential public health impact. Here, we review factors …

The development of rotavirus vaccines that are based on heterotypic or serotype-specific
immunity has prompted many countries to establish programs to assess the disease burden …

Rotavirus is the most common cause of severe diarrhoea in children worldwide and
diarrhoeal deaths in children in developing countries. Accelerated development and …

Rotavirus, the most common diarrheal pathogen in children worldwide, causes
approximately one third of diarrhea-associated hospitalizations and 800,000 deaths per …

Candidate rotavirus vaccines have been prepared with reassortant strains specifically to
protect against the 4 major rotavirus G serotypes (Gl-4). Many studies using P (VP4) …

Rotavirus is the most common cause of severe diarrhea worldwide. In developing countries,
rotavirus may cause 600,000 to 870,000 deaths each year, accounting for an estimated 20 …

Acute gastroenteritis is a major source of morbidity and mortality among young children in
developed and developing countries. Enteropathogenic viruses are regarded as particularly …

A German mining lake and the supplying surface waters, which are located downstream of a
sewage plant, were examined regarding their microbiological and virological quality …