Nanoplastics and human health: hazard identification and biointerface

H Lai, X Liu, M Qu - Nanomaterials, 2022 - mdpi.com
Nanoplastics are associated with several risks to the ecology and toxicity to humans.
Nanoplastics are synthetic polymers with dimensions ranging from 1 nm to 1 μm. They are …

[HTML][HTML] A mechanical perspective on phagocytic cup formation

D Vorselen, RLD Labitigan, JA Theriot - Current opinion in cell biology, 2020 - Elsevier
Phagocytosis is a widespread and evolutionarily conserved process with diverse biological
functions, ranging from engulfment of invading microbes during infection to clearance of …

Understanding the phagocytosis of particles: the key for rational design of vaccines and therapeutics

S Moreno-Mendieta, D Guillén… - Pharmaceutical …, 2022 - Springer
A robust comprehension of phagocytosis is crucial for understanding its importance in innate
immunity. A detailed description of the molecular mechanisms that lead to the uptake and …

Antibody-dependent cellular phagocytosis of HIV-1-infected cells is efficiently triggered by IgA targeting HIV-1 envelope subunit gp41

M Duchemin, D Tudor, A Cottignies-Calamarte… - Frontiers in …, 2020 - frontiersin.org
Antibodies mediate a broad array of non-neutralizing Fc-mediated functions against HIV-1
including antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular …

Distinct timing of neutrophil spreading and stiffening during phagocytosis

A Zak, S Dupré-Crochet, E Hudik, A Babataheri… - Biophysical …, 2022 - cell.com
Phagocytic cells form the first line of defense in an organism, engulfing microbial pathogens.
Phagocytosis involves cell mechanical changes that are not yet well understood …

[HTML][HTML] Using blinking optical tweezers to study cell rheology during initial cell-particle contact

K Berghoff, W Gross, M Eisentraut, H Kress - Biophysical Journal, 2021 - cell.com
Phagocytosis is an important part of innate immunity and describes the engulfment of
bacteria and other extracellular objects on the micrometer scale. The protrusion of the cell …

[HTML][HTML] The Role of Macrophages in Hepatocellular Carcinoma and Their Therapeutic Potential

ME Bannister, DA Chatterjee, S Shetty… - International Journal of …, 2024 - mdpi.com
Hepatocellular carcinoma (HCC) represents a significant clinical burden globally and is
predicted to continue to increase in incidence for the foreseeable future. The treatment of …

Single-phagosome imaging reveals that homotypic fusion impairs phagosome degradative function

Y Yu, M Jiao, Z Zhang, Y Yu - Biophysical Journal, 2022 - cell.com
Immune cells degrade internalized pathogens in vesicle compartments called phagosomes.
Many intracellular bacteria induce homotypic phagosome fusion to survive in host cells, but …

Phenotyping polarization dynamics of immune cells using a lipid droplet-cell pairing microfluidic platform

L Pinon, N Ruyssen, J Pineau, O Mesdjian… - Cell Reports …, 2022 - cell.com
The immune synapse is the tight contact zone between a lymphocyte and a cell presenting
its cognate antigen. This structure serves as a signaling platform and entails a polarization of …

Mannose-coated fluorescent lipid microparticles for specific cellular targeting and internalization via glycoreceptor-induced phagocytosis

B Dumat, L Montel, L Pinon, P Matton… - ACS Applied Bio …, 2019 - ACS Publications
In this work, we report on the development of mannose-coated fluorescent lipid
microparticles to study the role of C-type lectin membrane receptors in phagocytosis. The …