Lung cancer diagnosis is a challenge since it is also one of the most frequently diagnosed
cancers. Diagnostic challenges are deeply related to the development of personalized …

Cancer cells constantly face a fluctuating nutrient supply and interference with adaptive
responses might be an effective therapeutic approach. It has been discovered that in the …

Abnormal choline metabolism is emerging as a metabolic hallmark that is associated with
oncogenesis and tumour progression. Following transformation, the modulation of enzymes …

Background Recently, rapid advances have been made in metabolomics-based, easy-to-
use early cancer detection methods using blood samples. Among metabolites, profiling of …

The past decades of advancements in NMR have made it a very powerful tool for metabolic
research. Despite its limitations in sensitivity relative to mass spectrometric techniques, NMR …

The reorganization of metabolic pathways in cancer facilitates the flux of carbon and
reducing equivalents into anabolic pathways at the expense of oxidative phosphorylation …

Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …

Traditional Chinese medicine (TCM) is a holistic approach to health that attempts to bring
the body, mind and spirit into harmony. Entering 21st century, TCM is getting more and more …

Precision medicine is rapidly emerging as a strategy to tailor medical treatment to a small
group or even individual patients based on their genetics, environment and lifestyle …

Cancer cells are reprogrammed to utilize glycolysis at high rates, which provides metabolic
precursors for cell growth. Consequently, glucose levels may decrease substantially in …