Recent applications of fluorescence correlation spectroscopy in live cells

AW Smith - Current Opinion in Chemical Biology, 2024 - Elsevier
As a time-domain analogue of fluorescence imaging, FCS offers valuable insights into
molecular dynamics, interactions, and concentrations within living cells. The primary insight …

Combining fluorescence fluctuations and photobleaching to quantify surface density

J Sefkow-Werner, E Migliorini, C Picart… - Analytical …, 2022 - ACS Publications
We have established a self-calibrated method, called pbFFS for photobleaching fluctuation
fluorescence spectroscopy, which aims to characterize molecules or particles labeled with …

Both the transcriptional activator, Bcd, and repressor, Cic, form small mobile oligomeric clusters

L Zhang, L Hodgins, S Sakib, A Verbeem… - Biophysical …, 2024 - cell.com
Transcription factors play an essential role in pattern formation during early embryo
development, generating a strikingly fast and precise transcriptional response that results in …

Engineered Biomimetic platforms to analyse molecular and cellular role of Heparan Sulfate on BMP2 bioactivity

J Sefkow-Werner - 2021 - theses.hal.science
The extra cellular matrix (ECM) provides mechanical structure to embedded cells and gives
biochemical cues to regulate homeostasis and differentiation. The structural molecule …