Protein post-translational modifications (PTMs) profoundly influence protein functions and
play crucial roles in essentially all cell biological processes. The diverse realm of PTMs and …

Protein S-acylation, the only fully reversible posttranslational lipid modification of proteins, is
emerging as a ubiquitous mechanism to control the properties and function of a diverse …

Fatty acids (FAs) are essential nutrients, but how they are transported into cells remains
unclear. Here, we show that FAs trigger caveolae-dependent CD36 internalization, which in …

Protein S-palmitoylation is a reversible post-translational modification that regulates many
key biological processes, although the full extent and functions of protein S-palmitoylation …

Post-translational modifications (PTMs) occur in almost all proteins and play an important
role in numerous biological processes by significantly affecting proteins' structure and …

The iTRAQ (isobaric tags for relative and absolute quantification) technique is widely
employed in proteomic workflows requiring relative quantification. Here, we review the …

The lipid post‐translational modification S‐palmitoylation is a vast developing field, with the
modification itself and the enzymes that catalyse the reversible reaction implicated in a …

Double‐stranded DNA is recognized as a danger signal by cyclic guanosine
monophosphate‐adenosine monophosphate synthase (cGAS), triggering innate immune …

Hyperinsulinemia often precedes type 2 diabetes. Palmitoylation, implicated in exocytosis, is
reversed by acyl-protein thioesterase 1 (APT1). APT1 biology was altered in pancreatic …

Revised and updated, Chemical Reagents for Protein Modification, Third Edition is an
encyclopedic work describing the many approaches to the site-specific modification of …