DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

Cardiovascular disease is the leading cause of death worldwide, with this trend predicted to
continue for the foreseeable future. Common disorders are associated with the stenosis or …

Pluripotent stem cells (PSCs) hold great potential for novel therapeutic approaches to
regenerate or replace functionally impaired tissues. Since the introduction of the induced …

During the last decade biomaterial sciences and tissue engineering have become new
scientific fields supplying rising demand of regenerative therapy. Tissue engineering …

Tissue engineered vascular grafts (TEVGs) are beginning to achieve clinical success and
hold promise as a source of grafting material when donor grafts are unsuitable or …

Vascular smooth muscle cells (VSMCs) can be derived in large numbers from human
induced pluripotent stem cells (hiPSCs) for producing tissue-engineered vascular grafts …

Native grafts such as internal mammary artery and saphenous vein are the main choice for
coronary artery bypass graft. However, due to the limitations associated with their availability …

Rapid endothelialization of small-diameter vascular grafts remains a significant challenge in
clinical practice. In addition, compliance mismatch causes intimal hyperplasia and finally …

Derivation of functional vascular smooth muscle cells (VSMCs) from human induced
pluripotent stem cells (hiPSCs) to generate tissue-engineered blood vessels (TEBVs) holds …

Due to the lack of efficacy of synthetic vascular substitutes in the replacement of small-
caliber arteries, vascular tissue engineering (VTE) has emerged as a promising solution to …