Mycoplasma pneumoniae is an important cause of respiratory tract infections in children as
well as adults that can range in severity from mild to life-threatening. Over the past several …

Mycoplasmas as economically important and pantropic pathogens can cause similar clinical
diseases in different hosts by eluding host defense and establishing their niches despite …

Meta-analysis of gene expression data sets is increasingly performed to help identify robust
molecular signatures and to gain insights into underlying biological processes. The …

Identifying all essential genomic components is critical for the assembly of minimal artificial
life. In the genome‐reduced bacterium Mycoplasma pneumoniae, we found that small ORF s …

Translation is the fundamental process of protein synthesis and is catalysed by the ribosome
in all living cells. Here we use advances in cryo-electron tomography and sub-tomogram …

cis-Encoded antisense RNAs (asRNAs) are widespread along bacterial transcriptomes.
However, the role of most of these RNAs remains unknown, and there is an ongoing …

Our ability to build computational models that account for all known gene functions in a cell
has increased dramatically. But why build whole-cell models, and how can they best be …

Bacteria often use cyclic dinucleotides as second messengers for signal transduction. While
the classical molecule c-di-GMP is involved in lifestyle selection, the functions of the more …

The C‐terminal sequence of a protein is involved in processes such as efficiency of
translation termination and protein degradation. However, the general relationship between …

The human body is composed not only of human cells but is occupied by bacteria, archaea,
fungi, and viruses; this ensemble of organisms (microbiota) and their expressed genes are …