Antiaging Strategies and Remedies: A Landscape of Research Progress and Promise

R Tenchov, JM Sasso, X Wang… - ACS Chemical …, 2024 - ACS Publications
Aging is typified by a gradual loss of physiological fitness and accumulation of cellular
damage, leading to deteriorated functions and enhanced vulnerability to diseases. Antiaging …

[HTML][HTML] Targeting a mTOR/autophagy axis: A double-edged sword of rapamycin in spontaneous miscarriage

MY Li, HH Shen, XY Cao, XX Gao, FY Xu, SY Ha… - Biomedicine & …, 2024 - Elsevier
Immune dysfunction is a primary culprit behind spontaneous miscarriage (SM). To address
this, immunosuppressive agents have emerged as a novel class of tocolytic drugs …

Aging hallmarks and anti-aging strategies: a landscape of research advancement

R Tenchov, J Sasso, X Wang, QA Zhou - 2023 - chemrxiv.org
Aging is a dynamic, time-dependent process characterized by a gradual accumulation of cell
damage. Continual functional decline in the intrinsic ability of living organisms to accurately …

[PDF][PDF] Canagliflozin exerts anti-inflammatory and antioxidant effects in the heart and skin tissues: Biochemical and histopathological assessment in a model of …

AM Mahmood, AA Kassid, HH Al-Zuaini… - …, 2024 - pharmacia.pensoft.net
Canagliflozin was assessed for its anti-inflammatory and antioxidant effects as an anti-aging
drug in animal models. 50 Swiss albino male mice were divided into five groups; all groups …

What Could Explain Delay for Age-Reversal Clinical Trials?

W Faloon - International Journal of Translational …, 2024 - journals.riverpublishers.com
This is a commentary article using data reported by the United States Drug Approval (FDA)
system for clinical trials. The text surmised reasons for this delay. The data show continued …