Under stressful conditions, cellular heme catabolism to carbon monoxide, iron and biliverdin
is mediated by the 32 kDa enzyme, heme oxygenase-1 (HO-1). A wide range of pro-oxidant …

Lung endothelia in the arteries, capillaries, and veins are heterogeneous in structure and
function. Lung capillaries in particular represent a unique vascular niche, with a thin yet …

Objective To test whether systemic cytokine release is associated with central nervous
system inflammatory responses and glial injury in immune effector cell‐associated …

The majority of Alzheimer's disease (AD) cases are late-onset and occur sporadically,
however most mouse models of the disease harbor pathogenic mutations, rendering them …

In-vivo labeling of retinal amyloid-beta (Aβ) and tau has potential as non-invasive biomarker
for Alzheimer's disease (AD). However, literature on the presence of Aβ and phosphorylated …

Alzheimer's disease (AD) neuropathology is characterized by hyperphosphorylated tau
containing neurofibrillary tangles and amyloid-beta (Aβ) plaques. Normally these hallmarks …

Corpora amylacea (CA) have been described in several human organs and have been
associated with ageing and several pathological conditions. Although they were first …

There is growing evidence that air pollution is a risk factor for a number of
neurodegenerative diseases, most notably Alzheimer's (AD) and Parkinson's (PD). It is …

Lafora disease (LD), the most devastating adolescence‐onset epilepsy, is caused by
mutations in the EPM2A or EPM2B genes, which encode the proteins laforin and malin …

Monocarboxylate transporter 8 (MCT8) and organic anion transporter polypeptide 1C1
(OATP1C1) are thyroid hormone (TH) transmembrane transporters that play an important …