Global functions of O‐glycosylation: promises and challenges in O‐glycobiology

HH Wandall, MAI Nielsen, S King‐Smith… - The FEBS …, 2021 - Wiley Online Library
Mucin type O‐glycosylation is one of the most diverse types of glycosylation, playing
essential roles in tissue development and homeostasis. In complex organisms, O‐GalNAc …

Electrochemical aptasensors for cancer diagnosis in biological fluids–a review

A Díaz-Fernández, R Lorenzo-Gómez… - Analytica Chimica …, 2020 - Elsevier
The tunability of SELEX procedure is an essential feature to supply bioaffinity receptors
(aptamers) almost on demand for analytical and therapeutic purposes. This longstanding …

Impedimetric aptamer-based glycan PSA score for discrimination of prostate cancer from other prostate diseases

A Díaz-Fernández, R Miranda-Castro… - Biosensors and …, 2021 - Elsevier
Prostate specific antigen (PSA) is the common biomarker for prostate cancer (PCa).
However, its lack of specificity to differentiate PCa from benign prostate disorders stimulates …

A review on magnetic beads-based SELEX technologies: Applications from small to large target molecules

I Manea, M Casian, O Hosu-Stancioiu… - Analytica Chimica …, 2024 - Elsevier
This review summarizes the stepwise strategy and key points for magnetic beads (MBs)-
based aptamer selection which is suitable for isolating aptamers against small and large …

Aptamer-based signal amplification strategies coupled with microchips for high-sensitivity bioanalytical applications: a review

R Xu, Y Cheng, X Li, Z Zhang, M Zhu, X Qi, L Chen… - Analytica Chimica …, 2022 - Elsevier
With their advantages in specificity, high stability and easy screening, aptamers are
becoming increasingly popular recognition elements for biosensor platforms. At the same …

Challenges for impedimetric affinity sensors targeting protein detection

VP Gajdosova, L Lorencova, A Blsakova… - Current Opinion in …, 2021 - Elsevier
The review provides articles discussing big challenges behind successful design of
impedimetric biosensors and the way such challenges were/could be addressed for highly …

Efficient screening of glycan-specific aptamers using a glycosylated peptide as a scaffold

W Li, Y Ma, Z Guo, R Xing, Z Liu - Analytical Chemistry, 2020 - ACS Publications
Abnormal glycan structures are valuable biomarkers for disease states; the development of
glycan-specific binders is thereby significantly important. However, the structural homology …

Lectin-Mimicking Aptamer as a Generic Glycan Receptor for Sensitive Detection of Glycoproteins Associated with Cancer

I Díaz-Martínez, R Miranda-Castro… - Analytical …, 2024 - ACS Publications
The shortage of specific glycan recognition reagents has proven a significant hurdle in the
development of assays to detect altered glycoforms associated with cancer. Here, a …

High mannose-specific aptamers for broad-spectrum virus inhibition and cancer targeting

W Li, S Xu, Y Li, J Chen, Y Ma, Z Liu - CCS Chemistry, 2023 - chinesechemsoc.org
High mannose oligosaccharides are characteristic and essential for immune evasion of
many viruses and cancer cells. They are potential targets for viral inhibition and cancer …

Class-specific recognition and monitoring of environmental steroid estrogens in real water systems utilizing aptamer base substitution mutagenesis approach

S Liu, Z Wang, S Wu, T Cao, G Zhao - Journal of Hazardous Materials, 2024 - Elsevier
The same class of environmental steroid estrogens (SEs) with the highest estrogenic activity
share the same chemical core structure and are often found together in the environment …