Cardiovascular magnetic resonance (CMR) enables assessment and quantification of
morphological and functional parameters of the heart, including chamber size and function …

Fabry disease is an X-linked inherited lysosomal disorder that causes accumulation of
glycosphingolipids in body fluids and tissues, leading to progressive organ damage and …

The measurement of left ventricular ejection fraction (LVEF) is a ubiquitous component of
imaging studies used to evaluate patients with cardiac conditions and acts as an arbiter for …

Fabry disease (FD) is an X-linked lysosomal storage disorder caused by mutations of the
GLA gene that result in a deficiency of the enzymatic activity of α-galactosidase A and …

Background: Cardiac response to enzyme replacement therapy (ERT) in Fabry disease is
typically assessed by measuring left ventricular mass index using echocardiography or …

Background: Cardiovascular magnetic resonance can demonstrate myocardial processes in
Fabry disease (FD), such as low native T1 (sphingolipid storage) and late gadolinium …

Abstract Aims Cardiac involvement in Fabry disease (FD) occurs prior to left ventricular
hypertrophy (LVH) and is characterized by low myocardial native T1 with sphingolipid …

Cardiac MRI has become an indispensable imaging modality in the investigation of patients
with suspected heart disease. It has emerged as the gold standard test for cardiac function …

Fabry disease (FD) is a rare, X-linked inherited disorder of glycosphingolipid metabolism. It
leads to the progressive accumulation of globotriaosylceramide within lysosomes due to a …

Background The cardiac manifestations of Fabry disease are the leading cause of death, but
risk stratification remains inadequate. Identifying patients who are at risk of adverse cardiac …