Colistin Resistance in Acinetobacter baumannii: Molecular Mechanisms and Epidemiology

K Novović, B Jovčić - Antibiotics, 2023 - mdpi.com
Acinetobacter baumannii is recognized as a clinically significant pathogen causing a wide
spectrum of nosocomial infections. Colistin was considered a last-resort antibiotic for the …

Colistin heteroresistance in Acinetobacter spp.: systematic review and meta-analysis of the prevalence and discussion of the mechanisms and potential therapeutic …

S Karakonstantis, I Saridakis - International journal of antimicrobial agents, 2020 - Elsevier
Background: Colistin is one of the few remaining options for carbapenem-resistant
Acinetobacter baumannii (A. baumannii); however, emergence of resistance from …

Carbapenem-resistant Acinetobacter baumannii in US hospitals: diversification of circulating lineages and antimicrobial resistance

A Iovleva, MM Mustapha, MP Griffith, L Komarow… - MBio, 2022 - Am Soc Microbiol
Carbapenem-resistant Acinetobacter baumannii (CR Ab) is a major cause of health care-
associated infections. CR Ab is typically multidrug resistant, and infection is difficult to treat …

Synergistic effect of two antimicrobial peptides, Nisin and P10 with conventional antibiotics against extensively drug-resistant Acinetobacter baumannii and colistin …

A Jahangiri, A Neshani, SA Mirhosseini, K Ghazvini… - Microbial …, 2021 - Elsevier
Background Infections caused by drug-resistant strains of Acinetobacter baumannii and
Pseudomonas aeruginosa are now a global problem that requires the immediate …

Rapid microbial identification and colistin resistance detection via MALDI-TOF MS using a novel on-target extraction of membrane lipids

M Sorensen, CE Chandler, FM Gardner, S Ramadan… - Scientific Reports, 2020 - nature.com
Rapid infection diagnosis is critical to improving patient treatment and outcome. Recent
studies have shown microbial lipids to be sensitive and selective biomarkers for identifying …

[HTML][HTML] Comparative genomics and molecular epidemiology of colistin-resistant Acinetobacter baumannii

J Kabic, K Novovic, D Kekic, A Trudic, N Opavski… - Computational and …, 2023 - Elsevier
This study aimed to investigate the prevalence and resistance mechanisms of colistin-
resistant Acinetobacter baumannii (ColRAB) isolates in Serbia, assess their genetic …

[HTML][HTML] Phage-mediated colistin resistance in Acinetobacter baumannii

M Lucidi, F Imperi, I Artuso, G Capecchi… - Drug Resistance …, 2024 - Elsevier
Aims Antimicrobial resistance is a global threat to human health, and Acinetobacter
baumannii is a paradigmatic example of how rapidly bacteria become resistant to clinically …

Colistin Resistant A. baumannii: Genomic and Transcriptomic Traits Acquired Under Colistin Therapy

V Cafiso, S Stracquadanio, F Lo Verde… - Frontiers in …, 2019 - frontiersin.org
Even though colistin-based treatment represents the antimicrobial-regimen backbone for the
management of multidrug-resistant Gram-negative infections, colistin resistance is still rare …

A systematic review of implications, mechanisms, and stability of in vivo emergent resistance to colistin and tigecycline in Acinetobacter baumannii

S Karakonstantis - Journal of Chemotherapy, 2020 - Taylor & Francis
The potential of A. baumannii for acquired resistance to last resort antibiotics (colistin and
tigecycline) during treatment has important clinical implications, especially when dealing …

[HTML][HTML] Clinical, biological and genome-wide comparison of carbapenem-resistant Klebsiella pneumoniae with susceptibility transformation to polymyxin B during …

Y Wang, Q Luo, T Chen, X Chi, Y Zhou, H Fu… - Clinical Microbiology …, 2023 - Elsevier
Objectives The emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) is a
major clinical concern, and polymyxin B (PMB) is a 'last resort'antibiotic for its treatment …