Natural compounds as medical strategies in the prevention and treatment of psychiatric disorders seen in neurological diseases
E Küpeli Akkol, I Tatlı Çankaya… - Frontiers in …, 2021 - frontiersin.org
Psychiatric disorders are frequently encountered in many neurological disorders, such as
Alzheimer's and Parkinson diseases along with epilepsy, migraine, essential tremors, and …
Alzheimer's and Parkinson diseases along with epilepsy, migraine, essential tremors, and …
[HTML][HTML] Role of plant derived alkaloids and their mechanism in neurodegenerative disorders
Neurodegenerative diseases are conventionally demarcated as disorders with selective loss
of neurons. Conventional as well as newer molecules have been tested but they offer just …
of neurons. Conventional as well as newer molecules have been tested but they offer just …
[HTML][HTML] Therapeutic applications of mushrooms and their biomolecules along with a glimpse of in silico approach in neurodegenerative diseases
Neurodegenerative diseases (NDs) represent a common neurological pathology that
determines a progressive deterioration of the brain or the nervous system. For treating NDs …
determines a progressive deterioration of the brain or the nervous system. For treating NDs …
Identification of novel acetylcholinesterase inhibitors: Indolopyrazoline derivatives and molecular docking studies
The synthesis of novel indolopyrazoline derivatives (P1-P4 and Q1-Q4) has been
characterized and evaluated as potential anti-Alzheimer agents through in vitro …
characterized and evaluated as potential anti-Alzheimer agents through in vitro …
In silico studies in drug research against neurodegenerative diseases
FR Makhouri, JB Ghasemi - Current neuropharmacology, 2018 - ingentaconnect.com
Background: Neurodegenerative diseases such as Alzheimer's disease (AD), amyotrophic
lateral sclerosis, Parkinson's disease (PD), spinal cerebellar ataxias, and spinal and bulbar …
lateral sclerosis, Parkinson's disease (PD), spinal cerebellar ataxias, and spinal and bulbar …
Synthesis and biological evaluation of novel marine-derived indole-based 1, 2, 4-oxadiazoles derivatives as multifunctional neuroprotective agents
CS Jiang, Y Fu, L Zhang, JX Gong, ZZ Wang… - Bioorganic & Medicinal …, 2015 - Elsevier
Abstract Phidianidines (1), isolated from the marine opisthobranch mollusk Phidiana
militaris, present the first example of natural products possessing an 1, 2, 4-oxadiazole ring …
militaris, present the first example of natural products possessing an 1, 2, 4-oxadiazole ring …
Marine organisms as alkaloid biosynthesizers of potential anti-Alzheimer agents
E Lima, J Medeiros - Marine Drugs, 2022 - mdpi.com
The incidence of neurodegenerative diseases, such as Alzheimer's disease (AD), increases
continuously demanding the urgent development of anti-Alzheimer's agents. Marine …
continuously demanding the urgent development of anti-Alzheimer's agents. Marine …
Assessments of iodoindoles and abamectin as inducers of methuosis in pinewood nematode, Bursaphelenchus xylophilus
Bursaphelenchus xylophilus is a quarantined migratory endoparasite known to cause
severe economic losses in pine forest ecosystems. The study presents the nematicidal …
severe economic losses in pine forest ecosystems. The study presents the nematicidal …
Docking studies for multi-target drugs
The most basic principle of drug action is found in the lock and key model, where the highest
possible affinity for a target that also avoids side effects is desired. For many years this was …
possible affinity for a target that also avoids side effects is desired. For many years this was …
Enlarging the bottleneck in the analysis of alkaloids: A review on sample preparation in herbal matrices
LC Klein-Júnior, Y Vander Heyden… - TrAC Trends in Analytical …, 2016 - Elsevier
Alkaloids are a chemically diverse group of natural products known for their
pharmacological and toxicological effects. Plants are the best known source of these …
pharmacological and toxicological effects. Plants are the best known source of these …