[HTML][HTML] Appraising the causal role of smoking in multiple diseases: A systematic review and meta-analysis of Mendelian randomization studies

SC Larsson, S Burgess - EBioMedicine, 2022 - thelancet.com
Background The causal association between cigarette smoking and several diseases
remains equivocal. The purpose of this study was to appraise the causal role of smoking in a …

A tale of two diseases: Exploring mechanisms linking diabetes mellitus with Alzheimer's disease

J Lynn, M Park, C Ogunwale… - Journal of …, 2022 - content.iospress.com
Dementias, including the type associated with Alzheimer's disease (AD), are on the rise
worldwide. Similarly, type 2 diabetes mellitus (T2DM) is one of the most prevalent chronic …

The chronic neuropsychiatric sequelae of COVID‐19: The need for a prospective study of viral impact on brain functioning

GA De Erausquin, H Snyder, M Carrillo… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction The increasing evidence of SARS‐CoV‐2 impact on the central nervous system
(CNS) raises key questions on its impact for risk of later life cognitive decline, Alzheimer's …

[HTML][HTML] Nutrients and amyloid β status in the brain: A narrative review

G Díaz, L Lengele, S Sourdet, G Soriano… - Ageing Research …, 2022 - Elsevier
Amyloid beta (Aβ) is a peptide and a hallmark of Alzheimer's disease (AD). Emerging
evidence suggests that Aβ levels could be influenced by diet. However, the evidence is …

Immunomodulatory role of mesenchymal stem cells in Alzheimer's disease

L Zhang, Z Dong, J Zhang - Life sciences, 2020 - Elsevier
Alzheimer's disease (AD) is one of the most common causes of dementia and is
characterized by gradual loss in memory, language, and cognitive function. The hallmarks of …

[HTML][HTML] Earlier Detection of Alzheimer's Disease Based on a Novel Biomarker cis P-tau by a Label-Free Electrochemical Immunosensor

A Shiravandi, F Yari, N Tofigh, M Kazemi Ashtiani… - Biosensors, 2022 - mdpi.com
Early detection of cis phosphorylated tau (cis P-tau) may help as an effective treatment to
control the progression of Alzheimer's disease (AD). Recently, we introduced for the first time …

Direct inhibition of Keap1-Nrf2 Protein-Protein interaction as a potential therapeutic strategy for Alzheimer's disease

Y Sun, J Huang, Y Chen, H Shang, W Zhang, J Yu… - Bioorganic …, 2020 - Elsevier
The Kelch-like ECH-associated protein 1 (Keap1)-nuclear factor erythroid 2-related factor 2
(Nrf2) pathway works as the key regulator against oxidative stress damage in many cells …

Nutrition to prevent or treat cognitive impairment in older adults: a GRADE recommendation

F Buckinx, M Aubertin-Leheudre - The journal of prevention of Alzheimer's …, 2021 - Springer
Aging is associated with cognitive declines leading to mild cognitive impairments or
Alzheimer disease. Nutrition appear to protect from aging. Some dietary factors could either …

[HTML][HTML] Dietary and nutrient patterns and brain MRI biomarkers in dementia-free adults

A Drouka, E Mamalaki, E Karavasilis, N Scarmeas… - Nutrients, 2022 - mdpi.com
Cognitive impairment is a rapidly growing public health problem. As there is no curative
treatment for dementia, the proactive management of modifiable risk factors and the …

The beneficial role of natural endocrine disruptors: Phytoestrogens in Alzheimer's disease

A Domańska, A Orzechowski… - Oxidative Medicine …, 2021 - Wiley Online Library
Alzheimer's disease (AD) is the most common form of dementia with a growing incidence
rate primarily among the elderly. It is a neurodegenerative, progressive disorder leading to …