Lipid nanoparticles─ from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement

R Tenchov, R Bird, AE Curtze, Q Zhou - ACS nano, 2021 - ACS Publications
Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …

[HTML][HTML] Controlled drug delivery vehicles for cancer treatment and their performance

S Senapati, AK Mahanta, S Kumar… - Signal transduction and …, 2018 - nature.com
Although conventional chemotherapy has been successful to some extent, the main
drawbacks of chemotherapy are its poor bioavailability, high-dose requirements, adverse …

Liposomes as nanomedical devices

G Bozzuto, A Molinari - International journal of nanomedicine, 2015 - Taylor & Francis
Since their discovery in the 1960s, liposomes have been studied in depth, and they continue
to constitute a field of intense research. Liposomes are valued for their biological and …

Toward biocompatible semiconductor quantum dots: from biosynthesis and bioconjugation to biomedical application

J Zhou, Y Yang, C Zhang - Chemical reviews, 2015 - ACS Publications
The understanding of biological systems at the molecular scale is increasingly reliant on the
capability of tracking miscellaneous biomolecules and their events with improved spatial …

[HTML][HTML] Pharmaceutical formulations with P-glycoprotein inhibitory effect as promising approaches for enhancing oral drug absorption and bioavailability

TTL Nguyen, VA Duong, HJ Maeng - Pharmaceutics, 2021 - mdpi.com
P-glycoprotein (P-gp) is crucial in the active transport of various substrates with diverse
structures out of cells, resulting in poor intestinal permeation and limited bioavailability …

[HTML][HTML] Micro/nanoscale magnetic robots for biomedical applications

M Koleoso, X Feng, Y Xue, Q Li, T Munshi, X Chen - Materials Today Bio, 2020 - Elsevier
Magnetic small-scale robots are devices of great potential for the biomedical field because
of the several benefits of this method of actuation. Recent work on the development of these …

[HTML][HTML] Nanotheranostics˗ application and further development of nanomedicine strategies for advanced theranostics

MS Muthu, DT Leong, L Mei, SS Feng - Theranostics, 2014 - ncbi.nlm.nih.gov
Nanotheranostics is to apply and further develop nanomedicine strategies for advanced
theranostics. This review summarizes the various nanocarriers developed so far in the …

Utilizing the folate receptor for active targeting of cancer nanotherapeutics

GL Zwicke, G Ali Mansoori, CJ Jeffery - Nano reviews, 2012 - Taylor & Francis
The development of specialized nanoparticles for use in the detection and treatment of
cancer is increasing. Methods are being proposed and tested that could target treatments …

Lipid in chips: a brief review of liposomes formation by microfluidics

G Zhang, J Sun - International journal of nanomedicine, 2021 - Taylor & Francis
Liposomes are ubiquitous tools in biomedical applications, such as drug delivery,
membrane science and artificial cell. Micro-and nanofabrication techniques have …

Chitosan-g-estrone Nanoparticles of Palbociclib Vanished Hypoxic Breast Tumor after Targeted Delivery: Development and Ultrasound/Photoacoustic Imaging

AK Mehata, V Singh, Vikas, N Singh… - … Applied Materials & …, 2023 - ACS Publications
Breast cancer is the leading cause of death among women globally. Approximately 80% of
all breast cancers diagnosed are overexpressed with estrogen receptors (ERs). In this study …