Major challenges and perspectives in the diagnostics and treatment of dermatophyte infections
S Gnat, D Łagowski… - Journal of applied …, 2020 - academic.oup.com
Dermatophytes are the aetiological factors of a majority of superficial fungal infections. What
distinguishes them from other pathogenic filamentous fungi is their unique ability to degrade …
distinguishes them from other pathogenic filamentous fungi is their unique ability to degrade …
[HTML][HTML] Dermatophyte resistance to antifungal drugs: mechanisms and prospectus
Dermatophytes comprise pathogenic fungi that have a high affinity for the keratinized
structures present in nails, skin, and hair, causing superficial infections known as …
structures present in nails, skin, and hair, causing superficial infections known as …
Antifungal resistance mechanisms in dermatophytes
Although fungi do not cause outbreaks or pandemics, the incidence of severe systemic
fungal infections has increased significantly, mainly because of the explosive growth in the …
fungal infections has increased significantly, mainly because of the explosive growth in the …
Pathogenesis of dermatophytosis
S Vermout, J Tabart, A Baldo, A Mathy, B Losson… - Mycopathologia, 2008 - Springer
Despite the superficial localization of most dermatophytosis, host-fungus relationship in
these infections is complex and still poorly elucidated. Though many efforts have been …
these infections is complex and still poorly elucidated. Though many efforts have been …
Dermatophyte virulence factors: identifying and analyzing genes that may contribute to chronic or acute skin infections
RR Achterman, TC White - International journal of microbiology, 2012 - Wiley Online Library
Dermatophytes are prevalent causes of cutaneous mycoses and, unlike many other fungal
pathogens, are able to cause disease in immunocompetent individuals. They infect …
pathogens, are able to cause disease in immunocompetent individuals. They infect …
Generating and testing molecular hypotheses in the dermatophytes
Dermatophytes are the most common cause of fungal infections worldwide, impacting
millions of individuals annually. In the United States alone, this translates into an economic …
millions of individuals annually. In the United States alone, this translates into an economic …
[HTML][HTML] Trans-chalcone and quercetin down-regulate fatty acid synthase gene expression and reduce ergosterol content in the human pathogenic dermatophyte …
TA Bitencourt, TT Komoto, BG Massaroto… - … and alternative medicine, 2013 - Springer
Background Fatty acid synthase (FAS) is a promising antifungal target due to its marked
structural differences between fungal and mammalian cells. The aim of this study was to …
structural differences between fungal and mammalian cells. The aim of this study was to …
Differential gene expression in the pathogenic dermatophyte Arthroderma benhamiae in vitro versus during infection
P Staib, C Zaugg, B Mignon, J Weber… - …, 2010 - microbiologyresearch.org
Although dermatophytes are the most common agents of superficial mycoses in humans and
animals, the molecular basis of the pathogenicity of these fungi is largely unknown. In vitro …
animals, the molecular basis of the pathogenicity of these fungi is largely unknown. In vitro …
rpb2 is a reliable reference gene for quantitative gene expression analysis in the dermatophyte Trichophyton rubrum
The selection of reference genes used for data normalization to quantify gene expression by
real-time PCR amplifications (qRT-PCR) is crucial for the accuracy of this technique. In spite …
real-time PCR amplifications (qRT-PCR) is crucial for the accuracy of this technique. In spite …
[HTML][HTML] Transcriptional profiling reveals the expression of novel genes in response to various stimuli in the human dermatophyte Trichophyton rubrum
Background Cutaneous mycoses are common human infections among healthy and
immunocompromised hosts, and the anthropophilic fungus Trichophyton rubrum is the most …
immunocompromised hosts, and the anthropophilic fungus Trichophyton rubrum is the most …