Ethnopharmacological relevance Network pharmacology is a new discipline based on
systems biology theory, biological system network analysis, and multi-target drug molecule …

New research has shown that the development of osteoarthritis (OA) is regulated by different
mechanisms of cell death and types of cytokines. Therefore, elucidating the mechanism of …

The incidence of acute pancreatitis continues to increase worldwide, and it is one of the
most common gastrointestinal causes for hospital admission in the USA. In the past decade …

Programmed cell death has a vital role in embryonic development and tissue homeostasis.
Necroptosis is an alternative mode of regulated cell death mimicking features of apoptosis …

The pathogenetic mechanisms underlying neuronal death and dysfunction in Alzheimer's
disease (AD) remain unclear. However, chronic neuroinflammation has been implicated in …

Ruptured and intact plasma membranes are classically considered as hallmarks of necrotic
and apoptotic cell death, respectively. As such, apoptosis is usually considered a non …

Endothelium (EC) is a key component of blood–brain barrier (BBB), and has an important
position in the neurovascular unit. Its dysfunction and death after cerebral …

Ischemic stroke is one of the major causes of morbidity and mortality, affecting millions of
people worldwide. Inevitably, the interruption of cerebral blood supply after ischemia may …

Inflammasome is an intracellular signaling complex of the innate immune system. Activation
of inflammasomes promotes the secretion of interleukin 1β (IL-1β) and IL-18 and triggers …

Neutrophils or polymorphonuclear leukocytes (PMN) are key participants in the innate
immune response for their ability to execute different effector functions. These cells express …