Materials for oral delivery of proteins and peptides

TD Brown, KA Whitehead, S Mitragotri - Nature Reviews Materials, 2020 - nature.com
Throughout history, oral administration has been regarded as the most convenient mode of
drug delivery, as it requires minimal expertise and invasiveness. Although oral delivery …

Tailored mesoporous inorganic biomaterials: assembly, functionalization, and drug delivery engineering

Y Zou, B Huang, L Cao, Y Deng, J Su - Advanced Materials, 2021 - Wiley Online Library
Infectious or immune diseases have caused serious threat to human health due to their
complexity and specificity, and emerging drug delivery systems (DDSs) have evolved into …

Spherical mesoporous silica nanoparticles for loading and release of the poorly water-soluble drug telmisartan

Y Zhang, Z Zhi, T Jiang, J Zhang, Z Wang… - Journal of Controlled …, 2010 - Elsevier
The purpose of this study was to develop mesoporous silica nanoparticles (MSNs) loaded
with a poorly water-soluble drug, intended to be orally administered, able to improve the …

Functionalized ceramics for biomedical, biotechnological and environmental applications

L Treccani, TY Klein, F Meder, K Pardun, K Rezwan - Acta biomaterialia, 2013 - Elsevier
Surface functionalization has become of paramount importance and is considered a
fundamental tool for the development and design of countless devices and engineered …

Pore engineering of Porous Materials: Effects and Applications

A Wang, Y Ma, D Zhao - ACS nano, 2024 - ACS Publications
Porous materials, characterized by their controllable pore size, high specific surface area,
and controlled space functionality, have become cross-scale structures with …

[HTML][HTML] Multifunctional oral delivery systems for enhanced bioavailability of therapeutic peptides/proteins

Y Han, Z Gao, L Chen, L Kang, W Huang, M Jin… - … Pharmaceutica Sinica B, 2019 - Elsevier
In last few years, therapeutic peptides/proteins are rapidly growing in drug market
considering their higher efficiency and lower toxicity than chemical drugs. However, the …

Nature engineered diatom biosilica as drug delivery systems

UT Uthappa, V Brahmkhatri, G Sriram, HY Jung… - Journal of Controlled …, 2018 - Elsevier
Diatoms, unicellular photosynthetic algae covered with siliceous cell wall, are also called
frustule. These are the most potential naturally available materials for the development of …

Mesoporous systems for poorly soluble drugs

W Xu, J Riikonen, VP Lehto - International journal of pharmaceutics, 2013 - Elsevier
Utilization of inorganic mesoporous materials in formulations of poorly water-soluble drugs
to enhance their dissolution and permeation behavior is a rapidly growing area in …

Controlled release for crop and wood protection: Recent progress toward sustainable and safe nanostructured biocidal systems

BD Mattos, BL Tardy, WLE Magalhaes… - Journal of Controlled …, 2017 - Elsevier
We review biocide delivery systems (BDS), which are designed to deter or control harmful
organisms that damage agricultural crops, forests and forest products. This is a timely topic …

Mesoporous silica nanoparticles for increasing the oral bioavailability and permeation of poorly water soluble drugs

Y Zhang, J Wang, X Bai, T Jiang, Q Zhang… - Molecular …, 2012 - ACS Publications
We investigate the effects of spherical mesoporous silica nanoparticles (MSNs) as an oral
drug delivery system to improve the oral bioavailability of the model drug telmisartan (TEL) …