Several genetic disorders affecting bone mineralization may manifest during dentin
mineralization. Dentin and bone are similar in several aspects, especially pertaining to the …

Abstract Purpose of Review Osteogenesis imperfecta (OI) is a genetic bone disorder
resulting in bone fragility. It has a heterogeneous phenotype which typically includes …

Bisphosphonates (BPs) avidly bind to calcium crystals and inhibit osteoclastic bone
resorption, making them useful for treatment of skeletal disorders such as osteoporosis …

Mineralization of bones and teeth is tightly regulated by levels of extracellular inorganic
phosphate (Pi) and pyrophosphate (PPi). Three regulators that control pericellular …

Bisphosphonates are inhibitors of osteoclastic bone resorption with therapeutic benefit in a
variety of bone disorders in both adults and children. While these agents have been …

Tooth eruption is a pivotal milestone for children's growth and development. This process
involves with the formation of the tooth root, the periodontal ligament (PDL) and the alveolar …

Clastic cells are responsible for mineralized tissue resorption. Bone resorbing cells are
usually called osteoclasts; however, they are able to resorb mineralized dental tissues or …

OBJECTIVE: The objective of this paper was to analyse the effects of bisphosphonates and
their influence on orthodontic therapy. DATA/SOURCES: The literature was systematically …

To cite this article: Ghoneima AA, Allam ES, Zunt SL, Windsor LJ: Bisphosphonates
treatment and orthodontic considerations Orthod Craniofac Res 2010; 13: 1–10 Abstract …

Bisphosphonates (BPs) are potent inhibitors of osteoclastic bone resorption and widely used
for the treatment of osteoporosis and metastatic bone diseases. Recently, BPs have also …