Chemotherapeutics occupy a pivotal role in the medication of different types of cancers, but
the prevalence and mortality rates of cancer remain high. The drug resistance and low …

Thiazolidinedione (TZD) containing derivatives have been proved to be promising
anticancer agents in preclinical and clinical evaluation phases. Hybrid molecules not just …

Structural modifications of the antibacterial drug nitrofurantoin were envisioned, employing
drug repurposing and biology-oriented drug synthesis, to serve as possible anticancer …

In a sustained search for novel potential drug candidates with multispectrum therapeutic
application, a series of novel spirooxindoles was designed and synthesized via …

In the present study, two novel series of compounds incorporating naphthyl and pyridyl
linker were synthesized and biological assays revealed 5-((6-(2-(5-(2-chlorophenyl)-3-(4 …

In anticancer drug discovery, multi-targeting compounds have been beneficial due to their
advantages over single-targeting compounds. For instance, VEGFR-2 has a crucial role in …

Breast cancer is a disease in which cells in the breast divide continuously without control.
There are great limitations in cancer chemotherapy. Hence, it is essential to search for new …

Millions of people die of cancer every year, all around the world. Unfortunately, the
conventional chemotherapy is associated with some pharmacotoxicological …

The strategy implementing multitarget hybrid molecules as potential chemotherapeutic
agents to overcome resistance and increase efficiency is promising for different forms of …

Abstract Hexavalent chromium [Cr (VI)] is a widely distributed carcinogen in industrial
contexts and general environmental contexts. Emerging research highlights the central role …