Imaging biofilms using fluorescence in situ hybridization: seeing is believing
A Barbosa, S Miranda, NF Azevedo… - Frontiers in Cellular …, 2023 - frontiersin.org
Biofilms are complex structures with an intricate relationship between the resident
microorganisms, the extracellular matrix, and the surrounding environment. Interest in …
microorganisms, the extracellular matrix, and the surrounding environment. Interest in …
[HTML][HTML] The transcriptional regulators of virulence for Pseudomonas aeruginosa: Therapeutic opportunity and preventive potential of its clinical infections
In Pseudomonas aeruginosa (P. aeruginosa), transcription factors (TFs) are important
mediators in the genetic regulation of adaptability and pathogenicity to respond to multiple …
mediators in the genetic regulation of adaptability and pathogenicity to respond to multiple …
Machine-learning from Pseudomonas putida KT2440 transcriptomes reveals its transcriptional regulatory network
Bacterial gene expression is orchestrated by numerous transcription factors (TFs).
Elucidating how gene expression is regulated is fundamental to understanding bacterial …
Elucidating how gene expression is regulated is fundamental to understanding bacterial …
Advanced transcriptomic analysis reveals the role of efflux pumps and media composition in antibiotic responses of Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic pathogen and major cause of hospital-
acquired infections. The virulence of P. aeruginosa is largely determined by its …
acquired infections. The virulence of P. aeruginosa is largely determined by its …
Systems biology of competency in Vibrio natriegens is revealed by applying novel data analytics to the transcriptome
Vibrio natriegens regulates natural competence through the TfoX and QstR transcription
factors, which are involved in external DNA capture and transport. However, the extensive …
factors, which are involved in external DNA capture and transport. However, the extensive …
A multi-scale expression and regulation knowledge base for Escherichia coli
CR Lamoureux, KT Decker, AV Sastry… - Nucleic Acids …, 2023 - academic.oup.com
Transcriptomic data is accumulating rapidly; thus, scalable methods for extracting
knowledge from this data are critical. Here, we assembled a top-down expression and …
knowledge from this data are critical. Here, we assembled a top-down expression and …
Laboratory evolution, transcriptomics, and modeling reveal mechanisms of paraquat tolerance
Relationships between the genome, transcriptome, and metabolome underlie all evolved
phenotypes. However, it has proved difficult to elucidate these relationships because of the …
phenotypes. However, it has proved difficult to elucidate these relationships because of the …
A comprehensive review of genomics, transcriptomics, proteomics, and metabolomic insights into the differentiation of Pseudomonas aeruginosa from the planktonic …
Biofilm formation by Pseudomonas aeruginosa is primarily responsible for chronic wound
and lung infections in humans. These infections are persistent owing to the biofilm's high …
and lung infections in humans. These infections are persistent owing to the biofilm's high …
Compendium-wide analysis of Pseudomonas aeruginosa core and accessory genes reveals transcriptional patterns across strains PAO1 and PA14
Pseudomonas aeruginosa is an opportunistic pathogen that causes difficult-to-treat
infections. Two well-studied divergent P. aeruginosa strain types, PAO1 and PA14, have …
infections. Two well-studied divergent P. aeruginosa strain types, PAO1 and PA14, have …
The hallmarks of a tradeoff in transcriptomes that balances stress and growth functions
Fast growth phenotypes are achieved through optimal transcriptomic allocation, in which
cells must balance tradeoffs in resource allocation between diverse functions. One such …
cells must balance tradeoffs in resource allocation between diverse functions. One such …