Nonhuman primates have emerged as an excellent model of human tuberculosis, in large
part because they recapitulate the full spectrum of infection outcome and pathology seen in …

Major histocompatibility complex (MHC) gene products control the repertoire of T cell
responses that an individual may create against pathogens and foreign tissues. This text will …

Strain 68-1 rhesus cytomegalovirus expressing simian immunodeficiency virus (SIV)
antigens (RhCMV/SIV) primes MHC-E-restricted CD8+ T cells that control SIV replication in …

Hepatitis B virus (HBV) is a major global health concern, and the development of curative
therapeutics is urgently needed. Such efforts are impeded by the lack of a physiologically …

Major histocompatibility complex (MHC) class I alleles of nonhuman primates have been
associated with disease susceptibility, resistance, and resolution. Here, using high …

The importance of a broad CD8 T lymphocyte (CD8-TL) immune response to HIV is
unknown. Ex vivo measurements of immunological activity directed at a limited number of …

MHC-E is a highly conserved nonclassical MHC class Ib molecule that predominantly binds
and presents MHC class Ia leader sequence-derived peptides for NK cell regulation …

Background. Biomarkers of progression from latent Mycobacterium tuberculosis infection to
active tuberculosis are needed. We assessed correlations between infection outcome and …

The publication of research articles involving animal studies is central to many disciplines in
science and biomedicine. Effective descriptions in such publications enable researchers to …

Nonhuman primate (NHP) disease models for AIDS have made important contributions to
the search for effective vaccines for AIDS. Viral diversity, persistence, capacity for immune …