Paracetamol (APAP) is one of the most widely used and popular over-the-counter analgesic
and antipyretic drugs in the world when used at therapeutic doses. APAP overdose can …

The prevalence of inflammatory bowel disease (IBD) is increasing, which is concerning
because IBD is a known risk factor for the development of colorectal cancer. Emerging …

Liver diseases have been a common challenge for people all over the world, which
threatens the quality of life and safety of hundreds of millions of patients. China is a major …

Isorhamnetin is a hepatoprotective flavonoid molecule derived from the leaves and fruits of
Hippophae rhamnoides L. However, the protective effect of isorhamnetin on acetaminophen …

Goji berry is a lesser-known fruit species and its berries have been used in traditional
medicine for centuries as remedies to treat eye, liver, and kidney ailments, as well as for the …

Cadmium (Cd) intoxication in human occurs through inhalation of cigarette smoke and
ingestion of contaminated water and food. We investigated the role of nebivolol (NEB) in Cd …

Natural antioxidants present in fruits have attracted considerable interest due to their
presumed safety and potential nutritional value. Even though antioxidant activities of many …

During liver surgery, hepatic blood flow needs to be blocked in order to reduce bleeding,
which inevitably results in hepatic ischemia/reperfusion injury (HI/R). Paeoniflorin (PF) is the …

This study sought to assess the protective effects of resveratrol and avocado oil in relation to
paracetamol-induced hepatotoxicity in rats. The rats were divided into five groups, namely …

Despite the wide clinical indications, methotrexate (MTX) use is limited because of serious
side effects including liver toxicity. MTX was shown to cause tissue damage by mainly …