The lack of representation of diverse ancestral backgrounds in genomic research is well-
known, and the resultant scientific and ethical limitations are becoming increasingly …

The use of food products and functional foods to manage and treat several health conditions
is expanding globally. Garlic (Allium sativum) consumption is commonly used for its potential …

Abstract South Eastern Bantu-speaking (SEB) groups constitute more than 80% of the
population in South Africa. Despite clear linguistic and geographic diversity, the genetic …

Background Rapid epidemiological health transitions occurring in vulnerable populations in
Africa that have an existing burden of infectious and non-communicable diseases predict an …

Genetic associations for lipid traits have identified hundreds of variants with clear differences
across European, Asian and African studies. Based on a sub-Saharan-African GWAS for …

Based on evaluations of imputation performed on a genotype dataset consisting of about
11,000 sub-Saharan African (SSA) participants, we show Trans-Omics for Precision …

Atherosclerosis precedes the onset of clinical manifestations of cardiovascular diseases
(CVDs). We used carotid intima-media thickness (cIMT) to investigate genetic susceptibility …

Background The major risk factors for atherosclerotic cardiovascular disease differ by race
or ethnicity but have largely been defined using populations of European ancestry. Despite …

Background: African populations are characterised by diversity at many levels including:
demographic history, genetic ancestry, language, wealth, socio-political landscape, culture …

Background: There is a high and increasing prevalence of overweight and obesity in South
Africans of all ages. Risk factors associated with overweight and obesity must be identified to …