The secretion of biotechnologically or pharmaceutically relevant recombinant proteins into
the culture supernatant of a bacterial expression host greatly facilitates their downstream …

Bacillus subtilis, belonging to the type species of Bacillus, is a type of soil-derived, low% G+
C, endospore-forming Gram-positive bacterium. After the discovery of B. subtilis 168 that …

The group of exported proteins of a bacterium are those proteins that are sorted from the
cytoplasm to the bacterial surface or to the surroundings of the microorganism. In probiotic …

The twin-arginine protein translocation (Tat) system has a unique ability to translocate folded
and co-factor-containing proteins across lipid bilayers. The Tat pathway is present in …

Background High-throughput methods are widely-used for strain screening effectively
resulting in binary information regarding high or low productivity. Nevertheless achieving …

A number of Gram-positive bacteria are important players in industry as producers of a
diverse array of economically interesting metabolites and proteins. As discussed in this …

Abstract The Gram-positive bacterium Bacillus subtilis and some of its close relatives are
widely used for the industrial production of enzymes for the detergents, food, and beverage …

The twin-arginine translocation (Tat) pathway is a prokaryotic transport system that enables
the transport of folded proteins across the cytoplasmic membrane. The Tat pathway was …

Corynebacterium glutamicum (C. glutamicum) is a highly promising alternative prokaryotic
host for recombinant protein expression, as it possesses several significant advantages over …

The Gram-positive soil bacterium Corynebacterium glutamicum has a long tradition in
industry as a potent cell factory for the production of various amino acids. Besides this, in the …