Atherosclerosis is a lipid-driven inflammatory disease of the arterial intima in which the
balance of pro-inflammatory and inflammation-resolving mechanisms dictates the final …

Atherosclerosis is a chronic inflammatory response that increases the risk of cardiovascular
diseases. An in-depth study of the pathogenesis of atherosclerosis is critical for the treatment …

Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of fatty
deposits in the inner walls of vessels. These plaques restrict blood flow and lead to …

Background An uncontrolled inflammatory response is a critical pathophysiological feature
of sepsis. Mesenchymal stem cells (MSCs) induce macrophage phenotype polarization and …

Clinical development of bromodomain and extra‐terminal (BET) protein inhibitors differs
from the traditional course of drug development. These drugs are simultaneously being …

Cardiovascular disease is the leading cause of mortality worldwide, and atherosclerosis the
principal factor underlying cardiovascular events. Atherosclerosis is a chronic inflammatory …

Apoptotic cells are rapidly engulfed and degraded by phagocytes through efferocytosis.
Efferocytosis is a highly regulated process. It is triggered upon the activation of caspase …

Atherosclerosis is an inflammatory and multifaceted disorder resulting from the accumulation
of lipid droplets and several types of immune cells, including macrophages, T and B …

Acute coronary syndrome (ACS) is a major cause of acute death worldwide. Both innate and
adaptive immunity regulate atherosclerosis progression, plaque stability, and thrombus …

Abstract Background Apabetalone (RVX-208) is a bromodomain and extraterminal protein
inhibitor (BETi) that in phase II trials reduced the relative risk (RR) of major adverse cardiac …