Nowadays, orthodontic treatment has become increasingly popular. However, the biological
mechanisms of orthodontic tooth movement (OTM) have not been fully elucidated. We were …

The importance of the tumor microenvironment in cancer progression is indisputable, yet a
key component of the microenvironment—biomechanical forces—remains poorly …

In vitro models are invaluable tools for deconstructing the biological complexity of the
periodontal ligament (PDL). Model systems that closely reproduce the 3-dimensional (3D) …

Scleral extracellular matrix (ECM) remodeling is thought to play a critical role in the
pathogenesis of glaucoma. Mechanical strain induced by elevated intraocular pressure can …

During orthodontic tooth movement (OTM), periodontal ligament cells (PDLCs) receive the
mechanical stimuli and transform it into myofibroblasts (Mfbs). Indeed, previous studies have …

Background/Aims: Remodeling of fibrous and vascular tissues in the periodontal ligament
(PDL) around the tooth root was observed during tooth movement by orthodontic force …

Myofibroblasts are specialized cells that play a key role in connective tissue remodeling and
reconstruction. Alpha-smooth muscle actin (α-SMA), vimentin and tenascin-C are …

Yes‐associated protein (YAP) and transcriptional coactivator with PDZ‐binding motif (TAZ)
are transcriptional coactivators encoded by paratactic homologous genes, shuttle‐crossing …

Introduction In this study, we aimed to explore the expressions of α-smooth muscle actin,
collagen type I, collagen type III, and osteocalcin in the periodontal ligament (PDL) under …

Abstract α-smooth muscle actin (α-SMA) and tenascin-C are stress-induced phenotypic
features of myofibroblasts. The expression levels of these two proteins closely correlate with …