[HTML][HTML] Stem cell-based therapy for human diseases

DM Hoang, PT Pham, TQ Bach, ATL Ngo… - Signal transduction and …, 2022 - nature.com
Recent advancements in stem cell technology open a new door for patients suffering from
diseases and disorders that have yet to be treated. Stem cell-based therapy, including …

The role of the immune microenvironment in bone, cartilage, and soft tissue regeneration: from mechanism to therapeutic opportunity

Y Xiong, BB Mi, Z Lin, YQ Hu, L Yu, KK Zha… - Military Medical …, 2022 - Springer
Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

A paradigm shift in cell-free approach: the emerging role of MSCs-derived exosomes in regenerative medicine

S Moghadasi, M Elveny, HS Rahman… - Journal of translational …, 2021 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) due to their pro-angiogenic, anti-
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …

A review of the regulatory mechanisms of extracellular vesicles-mediated intercellular communication

YJ Liu, C Wang - Cell Communication and Signaling, 2023 - Springer
Extracellular vesicles (EVs) are small, membrane-bound structures that are released from
cells into the surrounding environment. These structures can be categorized as exosomes …

Development of extracellular vesicle therapeutics: Challenges, considerations, and opportunities

B Claridge, J Lozano, QH Poh… - Frontiers in Cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) hold great promise as therapeutic modalities due to their
endogenous characteristics, however, further bioengineering refinement is required to …

Exosomes as naturally occurring vehicles for delivery of biopharmaceuticals: insights from drug delivery to clinical perspectives

A Butreddy, N Kommineni, N Dudhipala - Nanomaterials, 2021 - mdpi.com
Exosomes as nanosized vesicles are emerging as drug delivery systems for therapeutics
owing to their natural origin, their ability to mediate intercellular communication, and their …

Stem cells and exosomes: new therapies for intervertebral disc degeneration

Z Krut, G Pelled, D Gazit, Z Gazit - Cells, 2021 - mdpi.com
Intervertebral disc degeneration (IVDD) occurs as a result of an imbalance of the anabolic
and catabolic processes in the intervertebral disc, leading to an alteration in the composition …

Tumor-derived extracellular vesicles: The metastatic organotropism drivers

J Rezaie, M Ahmadi, R Ravanbakhsh, B Mojarad… - Life Sciences, 2022 - Elsevier
The continuous growing, spreading, and metastasis of tumor cells depend on intercellular
communication within cells resident in a tissue environment. Such communication is …

A minimally invasive exosome spray repairs heart after myocardial infarction

J Yao, K Huang, D Zhu, T Chen, Y Jiang, J Zhang… - ACS …, 2021 - ACS Publications
Myocardial infarction (MI) remains the most common cause of death worldwide. Many MI
survivors will suffer from recurrent heart failure (HF), which has been recognized as a …

A bibliometric analysis of exosomes in cardiovascular diseases from 2001 to 2021

D Ma, B Guan, L Song, Q Liu, Y Fan, L Zhao… - Frontiers in …, 2021 - frontiersin.org
Background: Exosomes in cardiovascular diseases (CVDs) have become an active research
field with substantial value and potential. Nevertheless, there are few bibliometric studies in …