In the determination of the bioavailability of drugs administered orally, the drugs' solubility
and permeability play a crucial role. For absorption of drug molecules and production of a …

The success of platinum-based anticancer agents has motivated the exploration of novel
metal-based drugs for several decades, whereas problems such as drug-resistance and …

D-ɑ-tocopheryl polyethylene glycol succinate (Vitamin E TPGS or TPGS) has been
approved by FDA as a safe adjuvant and widely used in drug delivery systems. The …

Poly (lactic-co-glycolic acid)(PLGA) is one of the most successfully developed
biodegradable polymers. Among the different polymers developed to formulate polymeric …

Design and functionalization strategies for multifunctional nanocarriers (eg, nanoparticles,
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …

Endocytosis is a fundamental process in which eukaryotic cells internalise molecules and
macromolecules via deformation of the membrane and generation of membrane-bound …

d-α-tocopheryl polyethylene glycol succinate (Vitamin E TPGS, or simply TPGS) is a water-
soluble derivative of natural Vitamin E, which is formed by esterification of Vitamin E …

The evolution of polymer based nanoparticles as a drug delivery carrier via pharmaceutical
nano/microencapsulation has greatly promoted the development of nano-and micro …

The surface of a polymeric nanoparticle (NP) is often functionalized with cell-interactive
ligands and/or additional polymeric layers to control NP interaction with cells and proteins …

The effectiveness of anticancer agents may be hindered by low solubility in water, poor
permeability, and high efflux from cells. Nanomaterials have been used to enable drug …