Role of Hedgehog and Hippo signaling pathways in cancer: a special focus on non-coding RNAs
Despite advanced clinical and translational oncology research, mortality rates are still
increasing worldwide. Recently, a class of non-coding RNAs (ncRNAs), such as microRNAs …
increasing worldwide. Recently, a class of non-coding RNAs (ncRNAs), such as microRNAs …
The role of circular RNAs in pancreatic cancer: new players in tumorigenesis and potential biomarkers
Circular RNAs (circRNAs) are a newly identified class of non-coding RNAs (ncRNAs) which
show different structure compared to other RNAs in terms of their covalently closed ends. To …
show different structure compared to other RNAs in terms of their covalently closed ends. To …
tRNA-derived fragments in T lymphocyte–beta cell crosstalk and in type 1 diabetes pathogenesis in NOD mice
F Brozzi, C Jacovetti, C Cosentino, V Menoud, K Wu… - Diabetologia, 2024 - Springer
Aims/hypothesis tRNAs play a central role in protein synthesis. Besides this canonical
function, they were recently found to generate non-coding RNA fragments (tRFs) regulating …
function, they were recently found to generate non-coding RNA fragments (tRFs) regulating …
Circular RNAs: emerging modulators in the pathophysiology of polycystic ovary syndrome and their clinical implications
S Mazloomi, V Mousavi… - Current Molecular …, 2024 - ingentaconnect.com
Polycystic ovary syndrome (PCOS) is a prevalent endocrine/metabolic disorder in women of
reproductive age. PCOS is characterized by hyperandrogenism, polycystic ovary …
reproductive age. PCOS is characterized by hyperandrogenism, polycystic ovary …
Biological functions, mechanisms, and clinical significance of circular RNA in pancreatic cancer: a promising rising star
Q Chen, J Li, P Shen, H Yuan, J Yin, W Ge, W Wang… - Cell & bioscience, 2022 - Springer
Pancreatic cancer (PC) is a highly malignant solid tumor with insidious onset and easy early
metastasis. Despite tremendous efforts devoted to research in this field, the mechanisms …
metastasis. Despite tremendous efforts devoted to research in this field, the mechanisms …
Hsa_circ_0005915 promotes N, N-dimethylformamide-induced oxidative stress in HL-7702 cells through NRF2/ARE axis
Z Liu, Q He, Y Liu, Y Zhang, M Cui, H Peng, Y Wang… - Toxicology, 2021 - Elsevier
Abstract N, N-dimethylformamide (DMF) is an organic compound widely used in industrial
production processes as a solvent with a low evaporation rate. Excessive exposure to DMF …
production processes as a solvent with a low evaporation rate. Excessive exposure to DMF …
Research advances in the roles of circular RNAs in pathophysiology and early diagnosis of gestational diabetes mellitus
Y Zhang, S Ye, Y Li, J Chen, Y Zhang - Frontiers in Cell and …, 2022 - frontiersin.org
Gestational diabetes mellitus (GDM) refers to different degrees of glucose tolerance
abnormalities that occur during pregnancy or are discovered for the first time, which can …
abnormalities that occur during pregnancy or are discovered for the first time, which can …
Prognostic, Diagnostic, and Clinicopathological significance of circular RNAs in pancreatic Cancer: a systematic review and Meta-analysis
J Li, Z Ye, X Hu, S Hou, Q Hang - Cancers, 2022 - mdpi.com
Simple Summary Growing evidence shows that circRNAs are closely associated with the
clinicopathological characteristics of pancreatic cancer (PC) patients and might facilitate the …
clinicopathological characteristics of pancreatic cancer (PC) patients and might facilitate the …
Circular RNA ciRS-7 signature as a potential biomarker for the early detection of diabetes with Alzheimer's disease: a hypothesis
Abstract In the 1970s, Circular RNAs (CircRNAs) were first discovered in RNA viruses as
viroids and were initially assumed to be RNA splicing defects. The roles and topologies of …
viroids and were initially assumed to be RNA splicing defects. The roles and topologies of …
CircTP63 promotes cell proliferation and invasion by regulating EZH2 via sponging miR-217 in gallbladder cancer
S Wang, H Tong, T Su, D Zhou, W Shi, Z Tang… - Cancer cell …, 2021 - Springer
Background Gallbladder cancer (GBC) is the most common biliary tract malignancy and has
a poor prognosis in patients with GBC. CircRNA TP63 (circTP63) has been implicated in cell …
a poor prognosis in patients with GBC. CircRNA TP63 (circTP63) has been implicated in cell …