The development of a new therapeutic drug is a complex, lengthy and expensive process.
On average, only one out of 10,000-30,000 originally synthesized compounds will clear all …

With the rapid development of next generation sequencing technology, the amount of
biological sequence data of the cancer genome increases exponentially, which calls for …

Abstract Coronavirus Disease 2019 (COVID-19) is a sudden viral contagion that appeared
at the end of last year in Wuhan city, the Chinese province of Hubei, China. The fast spread …

This paper investigates multiscale interdependence between the stock markets of Germany,
Austria, France, and the United Kingdom. Wavelet energy additive decomposition was …

As the potential drug targets, G-protein coupled receptors (GPCRs) and nuclear receptors
(NRs) are the focuses in pharmaceutical research. It is of great practical significance to …

Background The Resonant Recognition Model (RRM) is a physico-mathematical model that
interprets protein sequence linear information using digital signal processing methods. In …

Now that the human genome has been sequenced, the measurement, processing, and
analysis of specific genomic information in real time are gaining considerable interest …

With a large number of DNA and protein sequences already known, the crucial question is to
find out how the biological function of these macromolecules is" written" in the sequence of …

The field of bioinformatics has become a major part of the drug discovery pipeline playing a
key role in improvement and acceleration of this time and money consuming process. Here …

Methods to determine peridiodicity in protein sequences are useful for inferring function.
Fourier transformation is one approach but care is required to ensure the periodicity is …