[HTML][HTML] Advances in antibody phage display technology
Phage display technology can be used for the discovery of antibodies for research,
diagnostic, and therapeutic purposes. In this review, we present and discuss key parameters …
diagnostic, and therapeutic purposes. In this review, we present and discuss key parameters …
Ligand-targeted theranostic nanomedicines against cancer
Nanomedicines have significant potential for cancer treatment. Although the majority of
nanomedicines currently tested in clinical trials utilize simple, biocompatible liposome …
nanomedicines currently tested in clinical trials utilize simple, biocompatible liposome …
Peptides as therapeutic agents: challenges and opportunities in the green transition era
G Rossino, E Marchese, G Galli, F Verde, M Finizio… - Molecules, 2023 - mdpi.com
Peptides are at the cutting edge of contemporary research for new potent, selective, and
safe therapeutical agents. Their rise has reshaped the pharmaceutical landscape, providing …
safe therapeutical agents. Their rise has reshaped the pharmaceutical landscape, providing …
Combinatorial peptide libraries: mining for cell-binding peptides
BP Gray, KC Brown - Chemical reviews, 2014 - ACS Publications
The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …
a unique cellular landscape specific to the type and state of the cell. Ligands that …
In vivo Phage Display: A promising selection strategy for the improvement of antibody targeting and drug delivery properties
AS André, I Moutinho, JNR Dias… - Frontiers in …, 2022 - frontiersin.org
The discovery of hybridoma technology, described by Kohler and Milstein in 1975, and the
resulting ability to generate monoclonal antibodies (mAbs) initiated a new era in antibody …
resulting ability to generate monoclonal antibodies (mAbs) initiated a new era in antibody …
Prohibitin ligands in cell death and survival: mode of action and therapeutic potential
F Thuaud, N Ribeiro, CG Nebigil, L Désaubry - Chemistry & biology, 2013 - cell.com
Prohibitins (PHBs) are scaffold proteins that modulate many signaling pathways controlling
cell survival, metabolism, and inflammation. Several drugs that target PHBs have been …
cell survival, metabolism, and inflammation. Several drugs that target PHBs have been …
Screening of specific binding peptides using phage-display techniques and their biosensing applications
Biosensors have been explored for their excellent potential in the field of biological detection
and their application in biomedical diagnosis and have become a rapidly emerging subject …
and their application in biomedical diagnosis and have become a rapidly emerging subject …
Design and proof of concept for targeted phage-based COVID-19 vaccination strategies with a streamlined cold-free supply chain
DI Staquicini, FHF Tang, C Markosian… - Proceedings of the …, 2021 - National Acad Sciences
Development of effective vaccines against coronavirus disease 2019 (COVID-19) is a global
imperative. Rapid immunization of the entire human population against a widespread …
imperative. Rapid immunization of the entire human population against a widespread …
Non-invasive early detection of acute transplant rejection via nanosensors of granzyme B activity
The early detection of the onset of transplant rejection is critical for the long-term survival of
patients. The diagnostic gold standard for detecting transplant rejection involves a core …
patients. The diagnostic gold standard for detecting transplant rejection involves a core …
The role of phage display in therapeutic antibody discovery
Phage display involves the expression of selected proteins on the surface of filamentous
phage through fusion with phage coat protein, with the genetic sequence packaged within …
phage through fusion with phage coat protein, with the genetic sequence packaged within …