[HTML][HTML] Desaturases and elongases involved in long-chain polyunsaturated fatty acid biosynthesis in aquatic animals: From genes to functions

Ó Monroig, AC Shu-Chien, N Kabeya, DR Tocher… - Progress in lipid …, 2022 - Elsevier
Marine ecosystems are rich in “omega-3” long-chain (C 20-24) polyunsaturated fatty acids
(LC-PUFA). Their production has been historically accepted to derive mostly from marine …

Long-chain polyunsaturated fatty acid biosynthesis in chordates: Insights into the evolution of Fads and Elovl gene repertoire

LFC Castro, DR Tocher, O Monroig - Progress in lipid research, 2016 - Elsevier
Long-chain polyunsaturated fatty acids (LC-PUFA) are major components of complex lipid
molecules and are also involved in numerous critical biological processes. Studies …

Regulation of long-chain polyunsaturated fatty acid biosynthesis in teleost fish

D Xie, C Chen, Y Dong, C You, S Wang… - Progress in Lipid …, 2021 - Elsevier
Abstract Omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA, C 20-24),
including eicosapentaenoic acid (EPA, 20: 5n-3) and docosahexaenoic acid (DHA, 22: 6n …

Desaturases and elongases involved in polyunsaturated fatty acid biosynthesis in aquatic invertebrates: a comprehensive review

Ó Monroig, N Kabeya - Fisheries Science, 2018 - Springer
Invertebrates represent a large proportion of the biomass in aquatic ecosystems, particularly
in the ocean. In recent years, invertebrates have been well-consolidated models in …

Requirements of n-3 very long-chain PUFA in Atlantic salmon (Salmo salar L): effects of different dietary levels of EPA and DHA on fish performance and tissue …

M Bou, GM Berge, G Baeverfjord, T Sigholt… - British Journal of …, 2017 - cambridge.org
Farmed salmon feeds have changed from purely marine-based diets with high levels of EPA
and DHA in the 1990s to the current 70% plant-based diets with low levels of these fatty …

Omega‐3 long‐chain polyunsaturated fatty acids in Atlantic salmon: Functions, requirements, sources, de novo biosynthesis and selective breeding strategies

Z Zhang, Y Miar, D Huyben… - Reviews in …, 2023 - Wiley Online Library
The aquaculture industry is a substantial user of wild‐sourced fish oil to supply omega‐3 (n‐
3) long‐chain polyunsaturated fatty acids (LC‐PUFAs) in fish diets, which are required by …

[HTML][HTML] Two alternative pathways for docosahexaenoic acid (DHA, 22: 6n-3) biosynthesis are widespread among teleost fish

A Oboh, N Kabeya, G Carmona-Antoñanzas… - Scientific reports, 2017 - nature.com
Docosahexaenoic acid (DHA) plays important physiological roles in vertebrates. Studies in
rats and rainbow trout confirmed that DHA biosynthesis proceeds through the so-called …

CRISPR/Cas9-mediated ablation of elovl2 in Atlantic salmon (Salmo salar L.) inhibits elongation of polyunsaturated fatty acids and induces Srebp-1 and target …

AK Datsomor, N Zic, K Li, RE Olsen, Y Jin, JO Vik… - Scientific reports, 2019 - nature.com
Atlantic salmon can synthesize polyunsaturated fatty acids (PUFAs), such as
eicosapentaenoic acid (20: 5n-3), arachidonic acid (20: 4n-6) and docosahexaenoic acid …

Functional Desaturase Fads1 (Δ5) and Fads2 (Δ6) Orthologues Evolved before the Origin of Jawed Vertebrates

LFC Castro, O Monroig, MJ Leaver, J Wilson, I Cunha… - PloS one, 2012 - journals.plos.org
Long-chain polyunsaturated fatty acids (LC-PUFAs) such as arachidonic (ARA),
eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids are essential components of …

Sustainable alternatives to dietary fish oil in tropical fish aquaculture

R Alhazzaa, PD Nichols, CG Carter - Reviews in Aquaculture, 2019 - Wiley Online Library
Marine tropical carnivorous (MTC) fish are less tolerant to high dietary lipid compared with
cold and temperate climate fish. However, insufficient n‐3 long‐chain (≥ C20) …